Aesculus and Centella, no they're not Gods
Aesculus and Centella
I almost didn’t post this for fear of the many that will ask, “Does it make your dick longer”? And “Did you gain any girth”? Anyway I am posting because I know there are many fine minds on here that will likely debate the topic (I hope).
Anyway it goes like this I get treatment from a Naturopath for unrelated problems, one of which is spider veins and swelling which induces a mottled discoloration, this is caused by blood being pushed from tiny capillaries and not being taken away by the lymph system (without going into too many details).
Now he gives me a cream Aesculus cream, which is Horse Chestnut extract cream, and this is to strengthen the capillaries and veins and close off some of the little holes that are letting out the corpuscles. Good stuff so I say “what the hell” and rub some on my cock, and after a few weeks there are very little red dots from jelqing, and no more broken capilleries giving me hard to explain purple spots.
All is good right? So I go back to him two months later and he asks is the mottling going away and say “Sort of, it already was with all the things I’m doing for circulation”, (which he knows about). He gets a bit of a furrow in the brow and starts’ going on about it’s all in the connective tissue remodelling, collagen, elastin and scar tissue repair (referring to the veins). Then he tells me he is going to add some Centella to the mix to help it along.
So I got home and looked it up and here is what I found.
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• Performing your original search, centella cream, in PubMed will retrieve 14 records.
New innovations in scar management - PubMed
Aesthetic Plast Surg. 2000 May-Jun;24(3):227-34.
New innovations in scar management.
Widgerow AD, Chait LA, Stals R, Stals PJ.
Abstract
As current aesthetic surgical techniques become more standardized and results more predictable, a fine scar may be the demarcating line between acceptable and unacceptable aesthetic results. With this in mind, a scar management program has been adopted based on the modalities of wound support, hydration, and hastened maturity, all factors gleaned from scientific evidence published over the past 25 years. Tension on a scar in one axis will result in a stretched scar, probably initiated by neutrophils and their neutral proteases [18,26]. Tension on a scar from many directions or intermittently will result in a hypertrophic scar, possibly initiated by lymphocytes but definitely related to a prolongation of the inflammatory process, with increased fibroblast activity and overabundant extracellular matrix secretion [24,26]. The common initiating factor is the tension on the scar, and the critical element needed to counteract this tension is scar support. Clinical experience has shown us that the most reliable way to support a scar is by using microporous tape. Hydration is a second beneficial influence on scar control and is the basis of the use of silicone sheeting and gel [7,29,36]. Alpha Centella cream has two main components. The first is an extract from the plant Bulbine frutescens. This increases hydration under the tape by leaving a layer of fatty vesicles of glycoprotein on the skin surface. This also has antibacterial properties. The second component is the principal terpenoids extracted from the Centella asiatica plant. These include asiatic acid, madecassic acid, and asiaticoside. Centella asiatica has been documented to aid wound healing in a large number of scientific reports [5,12,21,22,33,34,40]. The most beneficial effect appears to be the stimulation of maturation of the scar by the production of type I collagen [4,19] and the resulting decrease in the inflammatory reaction and myofibroblast production. Thus these components have been incorporated into the formulation of a scar management program. This publication reviews much of the available literature relating to scar management and describes the formulation and use of a scar management program based on this information.
PMID:
10890953
[PubMed - indexed for MEDLINE]
Formation and function of the myofibroblast during tissue repair - PubMed
J Invest Dermatol. 2007 Mar;127(3):526-37.
Formation and function of the myofibroblast during tissue repair.
Hinz B.
Source
Laboratory of Cell Biophysics, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. boris.hinz@epfl.ch
Abstract
It is generally accepted that fibroblast-to-myofibroblast differentiation represents a key event during wound healing and tissue repair. The high contractile force generated by myofibroblasts is beneficial for physiological tissue remodeling but detrimental for tissue function when it becomes excessive such as in hypertrophic scars, in virtually all fibrotic diseases and during stroma reaction to tumors. Specific molecular features as well as factors that control myofibroblast differentiation are potential targets to counteract its development, function, and survival. Such targets include alpha-smooth muscle actin and more recently discovered markers of the myofibroblast cytoskeleton, membrane surface proteins, and the extracellular matrix. Moreover, intervening with myofibroblast stress perception and transmission offers novel strategies to reduce tissue contracture; stress release leads to the instant loss of contraction and promotes apoptosis.
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Now I’m not sure this can get down as far as the Tunica, but I figure the skin is pretty thin down there so I’ll give it a try, and put the info up for discussion and see who can add some thoughts and insight into the topic. Any way I don’t miss the purple spots.
