papaverine cream--"miracle grow" for PE?

Could papaverine cream help in PE?

The below article has been cited several times in threads on this forum, but I haven’t found much pointed discussion about it.

(The article is copyrighted in a scientific journal, so I can’t post the article here, nor can I provide a link to it. But I’ll post the abstract and citation below.)

Here’s the gist of the article:

- A team of scientists separated pigs into 3 separate groups. Each pig, in each group, was implanted with a tissue expander (similar to those used by women who have undergone a mastectomy, for instance).
- Group A received papaverine locally at the site of tissue expansion via topical papaverine cream. Group B received papaverine via injection at the site of tissue expansion. Group C was the control group. (It received no special medicine.)
- The results, in order of greatest rate of tissue expansion: A, B, C.
- The scientists concluded that topical papaverine cream could be used to accelerate the rate of tissue stretching.

I am using an extender that relies on dynamic splinting to cause the penis to elongate and widen slightly (Penimaster). I also am using the Static Stretcher, a sort of ADS. These devices work very similarly to that of “traditional” plastic surgery tissue expanders.

I suppose my question is obvious: would putting papaverine cream on my stretched unit work the same way as it worked for the pigs?

I’m willing to be the guinea pig on this “experiment,” but I have no way to get 2% papaverine cream (the same used in the scientific experiment). Further, I have two other concerns:

1. What if the papaverine cream causes some unwanted side effect when it comes into contact with sensitive penis skin?

2. I am uncut. Would it be possible that the papaverine cream, if applied topically, would simply cause the foreskin to stretch and elongate (instead of the tunica, etc.)? I’d hate to end up with a 9 inch unit and 12 inch foreskin!

Does anyone have any knowledge or ideas to share? Any experience with papaverine cream (not injections or oral medication)?

Jet

P.S. Here’s the abstract and citation, in case anyone on a college campus wants to investigate:

“Accelerating tissue expansion by application of topical papaverine cream”
Plast Reconstr Surg. 2004 Oct;114(5):1166-9

Tang Y, Luan J, Zhang X

Southern 2 Ward, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ben670315@sina.com

Abstract: The rate of tissue expansion can be accelerated by papaverine through a special delivery system, according to an early report. Because the delivery system was complex and inconvenient, another means of administrating papaverine was tested to observe the rate of tissue expansion. In this study, 24 miniature pigs were divided equally into three groups. Four 150-ml silicone expanders were implanted into each pig in groups A and C. Four modified rectangular silicone expanders were also implanted into each animal in group B. During the expansion process, 1 g of 2% hydrochloride papaverine cream was applied topically onto the surface of each pig’s expanding skin in group A two times daily, and hydrochloride papaverine solution was injected into the outer shell of each modified expander in group B weekly. Group C acted as the control group. The mean sum of the first four times of saline water volume that was injected into the expanders was 142.42 +/- 5.6 ml in group A, 128.72+/-4.8 ml in group B, and 106.38+/-3.28 in group C. There were statistical differences among the three groups. The mean sum of volume saline water that was injected into hind expanders was 137.51 +/- 5.1 ml in group A, 120.35 +/- 3.6 ml in group B, and 102.63 +/- 4.76 ml in group C, and there was a statistical difference among the three groups as well. There was no statistically significant difference in the thickness of fibrous capsules among the three groups. This study shows that the rate of tissue expansion can be accelerated by topical application of papaverine cream, and the rate is better than the rate of tissue expansion induced by the special drug delivery system.

My personal sentiment is that given the fact that traditional PE methods really work, what’s the point in trying to speed it up if there are so many unknowns and possible unsavory side effects. In my opinion, with traditional PE we have an arsenal of time tested and proven methods that work if you have the patience to apply them properly. If it’s accelerated growth you want (as do I) then try doing what I’ve been doing- namely, skip the recovery days except for when you really, really need them and, if you’re feeling up to it do a double routine on some days. Another thing I would be suspicious about would be the fact that in your scenario, your growth is being assisted by chemicals when your dick is being stretched by an ADS device. Something about that strikes me as unnatural- the dick being chemically stimulated to grow while it’s extended. In traditional PE we are growing the structure of the entire penis a little at a time and in a way which, for my nickel, would seem to allow ALL of the structures of the penis (nerves, ligs, skin, etc.) to, “catch up” in synchronicity with each other. This, to my way of thinking, would make traditional PE methods far safer than any kind of, “magic bullet” approach- be it chemical, surgical, or whatever. Anyway, if you try this, good luck and I certainly hope you don’t wind up with that 12” of uncircumcised dangle!!! The image THAT put into my mind- ech!!! Happy growing.

Whats your routine wants?

If you were a pig, I’d say sign up and go for it.

There has been a lot of experimentation in the past ten years on transdermal delivery of penile vaso-dilators. They just don’t have this method refined yet. For now, stick with classic PE, is my advice.

I’d actually like to know what possible side effects there are and how you could get it. I’d be willing to try it ,as well, if there were no bad side effects. A little lycanthropy I can deal with but I don’t want headaches, intestinal cramping, sleepiness or something.

You wouldn’t mind being transformed into a wolf? Or is there another definition to lycanthropy?

Papaverine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

flushing (feeling of warmth)
sweating
headache
tiredness
dizziness
skin rash
upset stomach
loss of appetite
diarrhea
constipation
stomach pain

If you experience either of the following symptoms, call your doctor immediately:

yellowing of the skin or eyes
irregular heartbeat

This is about orally taken Papaverine . I would imagine other forms would be similar. I couldn’t find it in cream. The foreskin regrowth guys are into this study ,too. The site, from which I got the above list of side effects , also said it is used for ED treatments, as well. I’m going to keep checking. Faster gains are better!

Sure, you are right. That’s what lycanthropy is.
Dude, if I could do that at will I would have a blast! Just a howling good time! Ek ulfr, ulfr i skogi.
Unfortunately it doesn’t say shape shifting is a side effect.

Haha yeah wouldn’t be too bad would it? Damn I need to stop thinking so seriously all the time!

Thanks for the replies everybody. I’ll probably just stick to a classic PE routine, as avocet and wantsmore recommend. I’m too much of a chicken to try it, I think ;)

I don’t believe those side effects would apply to topical cream, but I could be wrong. Like most such creams, rashes may be possible (and other skin ailments), but I doubt much else.

For guys wanting to regrow foreskin, this really might help. (Although using it would be at your own risk, obviously, given the experimental nature of this treatment.) But I’d bet that it’s not the best for total penile expansion—e.g., ligs, veins, etc.—as wantsmore reasons.

I guess the idea of PE miracle grow is too good to be true. Oh well.

It would certainly change the meaning of kicking the pig skin.

Is papaverine commercially available in topical form? The only thing I could find was pure papaverine hydrochloride(solid form).

Interestingly enough those are all side effects of the human to wolf transformation as well.

I am sure they just compounded with another chemical to make it into topical form.

According to WebMD, papaverine is used to treat, “Lack of Blood Supply to the Brain, and Peripheral Vascular Disease.” Also according to WebMD, ” Papaverine is a vasodilator. It works by relaxing the muscles in the blood vessels.”

I would use the cream if given the opportunity. It appears the study is taking place in China. I am sure the Chinese doctors in charge would allow someone to give it a try. Unfortunately, I don’t live in China.

I got a good laugh from that buddy.

I am also interested to see the results of this product.