On Testosterone Estrogen and the Prostate
Enclosed is an excerpt from Eugene Shippen, M.D.’ book entitled “Testosterone Syndrome” which I highly recommend if you have not read it.
How Does Testosterone figure in All This?”
“We know that the prostate gland is hormonally sensitive not only to testosterone, but also to estrogen and a number of other hormones. Now, if the vague popular opinion that the male hormone is dangerous to the prostate gland were true, what we would expect to find in the scientific literature is some indication that a man whose testosterone level is high is at greater risk of prostate disorders that a man whose testosterone level is low, Lets look at this research.”
“One study, carried out be researchers at Johns Hopkins, followed the prostatic fortunes of more than fifty men, some of whom eventually developed prostate cancer or BPH and some of whom remained disease free. The study included lab reports on the men’s levels of test. Up to fifteen years before they developed (or failed to develop) disease. There was absolutely no connection between testosterone levels and development of illness.”
“ A couple of recent studies have also found no connection between test. Levels and PSA levels. And since PSA is the most reliable lab marker of prostate cancer risk, the absence of any relationship to test. Is reasurring.”
“These two studies were both measuring the relationship to prostatic enlargement rather than cancer; nonetheless, the implications are intriguing. The Japanese study found that the men with least prostate enlargement had higher test. levels. Conversely, the men whose prostates were enlarged had higher levels of estrogen. So striking were the relationships that the Japanese scientist concluded that estrogen levels are highly correlated with prostate size and volume. The American study done on 320 New England men with BPH severe enough to be surgically treated and 320 men without BHP found that men with higher estrogen levels were more likely to develop BPH- and that if the test. levels were also low, their risk was even higher.”
“ What we are seeing here is the prostatic side of the theme where higher estrogen levels characteristic of male aging seem to put men a greater risk of illness of many kinds. The male body does not adapt well to high blood levels of testosterone. And this problem changes is hormone conversion and hormone excretion. “
Thus BPH is correlated to increased estrogen and reduced testosterone.
Merlin