Originally Posted by pineconetx
I just got prescribed Adderall. I’m curious If anyone has had any positive or negative experiences while on it. I’ve read that some people get super high Libido on it while others it decreases their libido. The same can be said for erection quality.Lastly there’s a wild rumor I think.. That it can shrink your penis, but that sounds way far fetched.
I’m high hoping that very little to people have encountered low libido.
I’ve heard varying reports from a wide variety of men about their sexual health while on Adderall. Some appear to be positive, but those are mostly linked to increased libido in the first year or two of regularly taking it. Same with Ritalin. This, however, is not the concern with taking this kind of stimulant for a long period of time. You can easily increase your libido with natural methods if this is a concern. There are other sexual health issues that might be significantly impacted, so I’d carefully weigh the pros and cons, and whether or not you can live without taking stimulants (especially those with neurotoxicity to the dopaminergic system). Prolonged use / abuse could impact susceptibility to neurological diseases later in life.
As someone who’s done a couple years on Adderall, I can only speak from my experience and what I’ve discovered in my research regarding sexual health. In 2017 I was diagnosed with Peyronie’s Disease. Prior to that were the two years I took Adderall. Peyronie’s is a truly awful disease that all men are susceptible to. Upon researching the potential causes of PD, I was led to one of the primary causes in how it actually develops. No, it’s not Adderall, but it certainly may have played a role, and perhaps impacts sexual health in other ways not completely understood, nor rarely discussed.
MITOCHONDRIAL DYSFUNCTION: “Since the first mitochondrial dysfunction was described in the 1960s, the medicine has advanced in its understanding the role mitochondria play in health and disease. Damage to mitochondria is now understood to play a role in the pathogenesis of a wide range of seemingly unrelated disorders such as schizophrenia, bipolar disease, dementia, Alzheimer’s disease, epilepsy, migraine headaches, strokes, neuropathic pain, Parkinson’s disease, ataxia, transient ischemic attack, cardiomyopathy, coronary artery disease, chronic fatigue syndrome, fibromyalgia, retinitis pigmentosa, diabetes, hepatitis C, and primary biliary cirrhosis. Medications have now emerged as a major cause of mitochondrial damage, which may explain many adverse effects.
Amphetamine-like psycho-stimulants are associated with long-term decreases in markers for monoaminergic neurons, suggesting neuronal loss and/or damage within the brain. This long-term “toxicity” results from formation of free radicals, particularly reactive oxygen species (ROS) and reactive nitrogen species (RNS), although the mechanism(s) of ROS and RNS formation are unclear. Mitochondria are a major source of ROS and mitochondrial dysfunction has been linked to some neuro-degenerative disorders. Amphetamines also inhibit mitochondrial function, although the mechanism involved in the inhibition is uncertain.”
MD RELATIONSHIP TO SEXUAL HEALTH: MD is largely the cause of Peyronie’s Disease as far as a biological explanation goes (what specifically led to that in the first place is unknown in merely every circumstance). If one were to examine the plaque/scar tissue that developed in the penis, they will find MD, an inability to process glucose (because it’s essentially now been poisoned by glucose). All the reactive oxygen species that are produced inside the mitochondria are now compromised. If there is a shortage of beta hydroxybutyrate to combat TGF-Beta (the cytokine/ protiens), which is essentially what Peyronie’s is, as far as material substance. Mitochondrial damage IS indeed part of that equation, which can lead to erectile dysfunction, erectile quality, possible loss of length & girth (symptoms of Peyronie’s) from and an overall inability to heal properly from micro-traumas, fractures, or injuries that we typically disregard. For those actively engaged in the PE world, you want to be careful regardless; as some unintentional injuries could result in PD (depending on severity and physical health at the time).
All that said, some medications like Adderall can’t be attributed as causation, but there are some correlations, and something to be aware of. IF you find it necessary to take a medication such as this, I’d use it as an opportunity to be diligent about your overall health. Diet and exercise go without saying, but keeping yourself in a more consistent state of Ketosis will certainly be huge in combatting inflammation / adding more beta hydroxybutyrate to the equation. There isn’t enough evidence to suggest Adderall is any more responsible than the infinite possibilities out there, but I’d urge you to do your research and rule out as many variables as you can before committing to any medication with side effects. Many, are of course, unknown. It’s potential relationship to mitochondrial dysfunction can’t be ignored. It could be coincidental in my own experience, but I immediately stopped taking it upon understanding more about it.
Stay healthy, be mindful of changes to the mind/body, and please be careful with PE. Oh, also don’t have sex without full erections while your high or drunk. It’s an easy way to injure yourself. You do NOT want Peyronie’s Disease. It’s a dreadful, life-altering condition everyone should do their best to avoid. Cheers
