Originally Posted by Kyrpa
Probably not for the majority. The testicular atrophy preventing effect while on TRT can be negligible even. It is not so simple as the estrogen level in decisive role, if the clomifen works as a estrogen agonist or antagonist in hypogonal- testis axis.
While known for ability to keep the spermatogenesis alive while on TRT , the leydig cell activation crucial for intratesticular testosterone level maintenance remains intact. Which would be the key asset for the testicular volume restoration.
Literature does not back the clomifen on testicular volume maintaining effect while on exogenous testosterone.
There has been easy fixes on bro science for everything, but the hormonal balance is delicate and adding this or that by chance is not the way.
Kyrpa,
Everything we discuss will not necessarily be covered in scientific literature. “Bro sciences” are an observation of things which work or tend to work, without getting overanalytical about “why” it works.
That being said, many men are reporting real world results of clomid while on a mild cycle of testosterone yields full balls versus a loss of testicular mass which is normally observed on a testosterone cycle without clomid.
Another “bro science” we discussed in another thread was a man can get ED and poor flaccids, from being in relationship where his wife does not desire him, or that she acts masculine or dominant or in a relationship which is abusive in other ways. Many of us who have been talking on these matters believe that the noticed increase in “ED” cases in the last 20 years is use to a “power differential” that is shifting AWAY from man, thus his ED tends to be psychological, and not due to physical environent changes.
Another “bro science”. If you are not sexually active while on testosterone your flaciid will also not be as full. However if you are sexually active the flaccid and erection may be enhanced. ( Masterbation does not count nor does it help ). When you come off of testosterone and the body starts producing testosterone naturally the flaccid will hang larger and the balls will become naturally “full” again.