FWIW, I took Nolvadex for 2 months and it didn’t affect my nut size at all. No difference in loads either.
Clomid and Nolvadex are selective estrogen receptor modulators. They bind to estrogen receptors. In some tissues they have an estrogenic effect (acting like estrogen) and in others they don’t do anything except plug up the receptor to prevent estrogen from binding. It’s sort of like putting a blank key in a lock to prevent a real key from being inserted.
The regulatory system is fooled into thinking estrogen is low. Estrogen is one of the feedback mechanisms for testosterone production. T production goes up (not necessarily free T because SHBG probably rises to compensate) and more of it converts to estrogen. So the actual estrogen levels are higher when on these drugs.
I don’t remember if they also have a minor effect on stimulating GnRH. Doesn’t really matter. The anti-estrogen aspect is responsible for at least most of their action.
Arimidex and similar drugs actually lower estrogen levels. Don’t fool with those (or any of this really) unless there is a need and you work with your doctor. Estrogen in the proper amounts is necessary and vital for the health of certain tissues.
Clomid and Nolvadex are often used by guys taking anabolic steriods. Nolva in particular is good at blocking the effects of estrogen in breast tissue and is often taken during a cycle to prevent gynecomastia (bitch tits).
Either one, though the preference has traditionally been for Clomid, can be used as part of a post-cycle program to restart natural testosterone production. If your nuts are withered from ‘roids, of course they’ll “get bigger,” aka return to normal size, when they resume producing normal amounts of testosterone. I think this is where the myth that Clomid will increase nut size began. Unless your nuts are atrophied from a cycle or you have some other medical reason to take them, why bother with these drugs? I doubt they’ll produce any noticeable effects.
If you try Clomid and experience any vision problems, stop taking it immediately to avoid potentially permanent eye damage.