Originally Posted by marinera
So you are suggesting that existing cells will be bigger after regeneration (hypertrophy), not that more cells are added to existing cells (hyperplasia)?
No this is not what I said. I said, “Tissue injury either heals by restoration of existing cells (whether as they were prior or bigger, depending upon the conditions that exist) or by replacement of cells that die.”
By restoration I mean repair. Cells have this capacity. If this cell is under stress, this may result in hypertrophy.
By replacement I meaning new cells (hyperplasia).
The production of new cells (by stimulation of locally produced factors) probably off load stress on existing cells (injured and repaired or uninjured) so that hypertrophy may not be the ultimate result.
Originally Posted by marinera
Also, you are supposing that if too much tissue damage is caused, than the tissue can’t be totally regenerated and scar (not useful) tissue is what we get?
No I said “if scar formation occurred after every episode of micro- or small injury, we’d all be one big scar. Does every cut you’ve ever had scar? I contend that most of the injury induced by PE is not injury repair by scar formation but by regeneration. I know we don’t regrow tails like lizards but we do have some capacity to regenerate.”
When I look at my body, I don’t see one large scar. Over the course of my life I’ve had lots of cuts, scrapes and bruises. This is a testament to restoration occurs in most cases without scaring
I don’t think that I am supposing what you suggest. However, total regeneration is not a normal process in humans (except to some small degree with severed finger tips that are allowed to heal without sutures of surgery).
Too much damage is a relative term. Repairing or replacing injured cells in an intact ligament or tunica by regeneration is the rule, not the exception. But there is a finite limit. If an injury say severs the suspensory ligament, I can guaranty you that repair will not result in an intact ligament without scar.
I would believe that you would not like to test the regenerative possibilities of the body by chopping off your penis and seeing if it regenerates. I contend there is a limit.