What is the consensus of chemical PE in 2020?

So…lots of time has passed since first pioneers of chemical PE in 2008…apparently many gained A LOT with PGE-1 and IGF.

However, can any people doing chemical PE in recent years report here with any gains?

If yes, what was your routine? How much did you gain?

I’m asking, because I’m using Caverject / Alprostadil for treatment of ED now and I think I could combine it with stuff like MK677 to actually get some gains.

But I would like to know more from people who have had actual success with this.

I think it makes sense to talk about the effect of individual chem PE substances alone or in combination.

Definitely not everything tried experimentally works. I’m not confident I can attribute anything to chem PE yet.

I’ve been experimenting with it, but not using the conventional substances mentioned in patents.

While the substances mentioned in the various threads are admirable for choosing substances that do one particular known thing, something like cell proliferation is a complicated affair with many different actors and cascades of cellular events.

I’m just critical of the methodology. We already know the penis can grow. The goal of screening chem PE substances isn’t to prove the penis can grow, it’s to find substances that make it grow. So why start with such a small pool of difficult to obtain substances, like PGE-1, potaba, and IGF, when there are so many other substances that upregulate these substances, which may or may not even contribute to growth independently? And why start with the more expensive substances first? And why not start with substances that have known systemic and/or histological toxicology profiles that are low risk? Why not use whatever data you already have on hand to try to tease out why some guys have much bigger penises while trying to control for genetic variability?

I have found a few things that seem promising so far and rejected many many others, but I’m very against the idea of spreading misinformation. Then there is the whole ethical dilema of creating penis arms race that I haven’t resolved.

Check out Ultra Hard and IconoGenin from Iconic Formulations. UH has 375mg of EpiAndrosterone per serving size, and eipiandrosterone is a metabolite of DHEA that is converted to DHT by the 5-a reductase enzymes in your skin. IE, UltraHard in and of itself might be THE solution for chemical PE since obtaining topical testosterone (this also causes direct penile growth by the same enzyme as it converts to DHT) requires a prescription from a doctor which means your test levels have to already be low. Unfortunately that’s not a problem I have.

And at 375mg.. That’s a lot. I might only use 2 or 3 pumps of that stuff at a time. Even a 20% topical testosterone PLO only has 200mg of test in it, and 70% of that is converted to DHT through the skin meaning 140mg becomes DHT. I heard a reputable endocrinologist talking about this on a podcast series I follow on MikeMahler.com, the guy’s name is Dr. Mark Gordon in case anyone wants to hear him talk. I forgot which podcast number it was and he’s been on the podcast several times in the past, but it was a few years ago when I heard it. He prescribed a 10% PLO (100mg test) to a black male patient and he had notable gains from it that stayed after only a few months of use. He said that DHT in the penis causes extra growth of blood vessels which is what causes the size enhancement.

I will report back with my findings. I’m ordering now and with a 25% military discount it’s well worth the price.

I have never done chem PE and would never but I was reading the other chem PE threads and pretty much just amazed that some guys actually shoot up these chemicals into their dicks. It definitely takes a leap of faith and a fearless mind to do so. After reading, I only read one guy saying he got some girth gains but other than that just a lot of guys having injuries and erections lasting way too long. A couple guys ended up in the ER and surgery beds, For guys who have really bad ED and Viagra and/or Cialis may not be an option because of allergies (or whatever reason) then these drugs prescribed by a urologist seem to have a a very good effect at low doses. This really seems to be the only extent of their use in a positive form. As far as for any kind of recreational aid to PE it seems not only ineffective but a really good way to find yourself in a hospital with your penis in a sling hoping and praying there’s no long term negative effects. It’s a bad idea to shoot your penis up with chemicals, IMO.

I don’t post often but thought that was worth saying.

Hi did this work? And do you apply it directly to your dick?

Chem PE simply does not work.