Witches' Brew for my Ape Brain Plus

I am in one of my cyclical funks yet again. Anyhow, I am brain doping myself starting today with:

GABA 750 mg tablets x 2 once a day γ-Aminobutyric acid - Wikipedia

Tyrosine 500 mg tablets x 4 once a day Tyrosine - Wikipedia

DMAE 25 mg tablets x10 once a day Dimethylethanolamine - Wikipedia

5-htp 50 mg tablets x 2 once a day 5-Hydroxytryptophan - Wikipedia

SAMe 400mg x1 once a day S-Adenosyl methionine - Wikipedia

Lexapro 10mg once a day Escitalopram - Wikipedia as ordered by my doctor

I also take 7200mg of Fish oil each day Fish oil - Wikipedia

900 mg of Turmeric Turmeric - Wikipedia for the past 6 months plus, sometimes double the dosage as it has certain anti-inflamatory properties I need for other reasons.

I also followed an anti-fibromyalgia protocol of vitamins A, B, C, E, Selenium, Magnesium, and Calcium.

I also take acidolpholus as a probiotic.

I have a Super B complex as well as a Multi I use for all around. I used to take the individual Bs seperately, but got tired of them running out at different frequencies and prices, etc…

I used to take St John’s Wort, but it appears that I got the super photo-reactive effect in my eyes from it. I have now had one ophthalmologist say I have starting cataracts in both my eyes. he claims it is not from this but one can google people claiming that it does.

I asked to be put on a MAO inhibitor (specifically a MAO-B) or a Tricylic, but my 500lb doctor ( I shit you not) writes me for lexpro which is supposed to be newer and some type of super selective serotonin mind fucker. I am in the beginning of my second week’s worth of the drug, so i have 20 plus days left of it.
Monoamine oxidase inhibitor - Wikipedia
Tricyclic antidepressant - Wikipedia

I was debating whether to add the following:

http://en.wikip … /Rhodiola_Rosea
Chromium - Wikipedia
http://en.wikip … a.org/wiki/Zinc
Eleutherococcus senticosus - Wikipedia
Ginkgo biloba - Wikipedia

So does anyone have any experience with any of this?

I would assume that the MAO qualities of the supplements are what I should watch out for.

Holy shit man! That’s a whole lot of drugs/supps. How are you ever going to tell what’s causing you any side effects you experience? I’ve had some nasty reactions to even supposedly innocuous substances, so I’d be careful if I were you. At least run this all by your 500 lb doctor. He may not endorse your regimen, and you can keep taking it even if he thinks it’s largely placebos, but he’d at least be helpful for letting you know whether you’re running the risk of known interactions.

My Doctor whom we shall refer to as Beefy Tits, wants me to take nothing but fucking Lexapro, Xanex, and fucking Lipitor. My fucking cholesterol after 4 grand in blood work said I am 40 points over acceptable range. So Shamu is worried I might have heart disease ten to twenty years down the line as the real priority instead of me stabling someone in the next 15 minutes with a toothbrush in the eye after they ring my doorbell and interrupt me on my daily delousing rituals.

I had no problems until the third or fourth day of the Lexapro, in which my eyes will try and close with this head drowsiness, if I fight through it for 2 plus hours, I then get insomnia for the next 12 to 18 hours. So since then I dialed back the SAM-e and 5-htp levels in half.

After taking an anti-fibromyalgia protocol my general aches and pains were cut in half to 2/3rds.

The GABA, tyrosine, and DMAE are all 36 hours or under in me for the first time.

I JUST added GINKO B, Chromium, and Zinc in since I typed this first post in the thread. Walgreen’s has 2 for 1 specials on in house brands, awesome for me, eh?

Doctor Lunchbox, refuses to write any other script barring a coma from the Lexapro, till the first month is up. I did get a referral for my old ass doctor whom I had 10 years ago from Jabba, so in February, hopefully I can get a new script of something the fuck else.

I could take nothing and just fucking chain-smoke instead. But I have yet to give in.

BIG BRAIN, I weigh 300lbs and am a snatch hair under a full 7’. So my level of tolerances are not the same as the average Joe for most shit.

http://depressi on.about.com/gi … 3Dpubmed_docsum

Taking so much shit is really a waste of time and health, pretty poor. If you were a real man with a fat pair of bollocks you would fight against your sickness yourself, not believing that 50 kind of different bullshit is going to do the work for you.

“All we got is us”, and you seem to have lost all faith in youself. So keep on having faith in all this supplements religion…

Believe me, you would get more benefit spending all that ‘supplement’ money in a good psychiatrist.

Too expensive my friend, too fucking expensive. Even with insurance in America, crazy doctors are out of the league of many. Even though Joe Blow Clinicians do see the majority of their patients complaining about some emotional related problem with the average visit. I don’t have the luxury of being born into a country with Socialized medicine, nor a place that stops for a siesta to keep it real either.

Woe is me.;)

I do agree that he needs a more thorough consultation on his psychiatric drugs. MAOI’s are not often prescribed anymore, and it’s even more rare to be prescribed that in addition to an SS/SN-RI; additionally, St. Johns Wort is generally not taken in combination with other psychiatric drugs —- I’d further investigate these matters.

That said, I’m not too opposed to psychiatric drugs. I’ve been on quite a few, and while my results haven’t been too reassuring, I have strong reasons to believe that I’m not an ordinary case. Unfortunately there is no way to ascertain what we are afflicted with, but some of us just know that we are likely "different" to our disadvantage, and most others simply will not understand this. To fight this on our own w/o exogenous help of some sort is to alter our brain-chemistry by what? Our own will to improve?

I think that I can help myself to some degree, and I can also experiment and adhere to activities which I believe to be most beneficial (always changing), but beyond that.some outside help is needed.

I’m quite interested in supplements based upon solid research: Nootropics, avoiding mineral deficiency, other active ingredients..
Although I have quite a few supplements and sources, and tons more which I’ve considered, I’ve decided not to be overzealous about my purchases and simply rely on my research.

For people with psychiatric issues (note that I so not use ALL of these supplements):

- Tyrosine and 5-htp; If you are on psychiatric drugs.you might want to experiment with these thoroughly before permanently adding them to your regiment. These interfere with brain chemistry. If on an SSRI then you must note that 5-htp crosses the blood/brain barrier and may further boost serotonin levels. Tyrosine may have a large effect on dopamine (and other) levels. The regulation of neurotransmitters is not fully understood either - these may help/hurt you depending on your chemistry.. Experiment (however a lot of doctors will tell you to just avoid them - they’re afraid of a lawsuit.I don’t trust the average dr)

-DMAE and GABA.. Hopefully GABA is helping to calm you. Phenibut is a more potent alternative to GABA. Be aware that these also may not suit you in the longterm. DMAE is generally beneficial. A supplement known as centrophenoxine reportedly has similar and subjectively better effects.

- Getting plenty of zinc is a good idea, however if you are taking more than 35mg or so, be sure you are getting enough copper (at least 2mg). Excess of one creates a deficiency in the other.

- Hopefully your multivitamin (I use "orthocore" purchased from unique nutrition, used "nature’s way ‘alive’ previous to that, purchased from iherb) is providing adequate levels of vits/minerals. Magnesium/Ca/Zinc are often deficient. Some chromium/selenium can be added w/o harm. On that note: a Vanadium deficiency (measured through hair) has been linked to psychiatric disorders (specifically bi-polar). High doses of Lithium have been prescribed for bi-polar as well.

- Coq10 (100mg; iherb has decent deals on japan-source coq10) and idebenone (coq10 derivative; bulknutrition has a good deal, bodybuilding may also - they offer unique nutrition products for less than U.Nut do) are especially recommended for "brain health."

- Getting enough vitamin d3 (actually a hormone really.. Produced from sunlight) is crucial.

- A regular sleep cycle is crucial. (Yea, I’m typing this a 5:30 am.. Haven’t slept yet. This is, however, part of my condition. You’d think I could just knock out.not so). Melatonin (1-3mg at most; is supposed to help, and it’s important to regulate this hormone).

- Ginkgo.. I use it. If taken for extended periods it may cease to have an effect..
- Ginkgo is commonly coupled with vinpocetine (powerful brain bloodflow) and huperzine A
- Sulbutiamine is known to decrease reaction time.. Benfotiamine is another related solube b-1 vit.
- ‘Racetams.. Piracetam, aniracetam, oxiracetam, etc.. Have been shown to be neuro-protective and seem to alter the blood-flow patterns of the brain, promoting greater exchange between hemispheres. Some people feel a little weird on this. Piractem is the most tested (used in japan since ‘60’s)

- Cholinergic agents.. Anything with an effect on choline.. Can be beneficial in small amounts. Alpha-GPC is potent but not well-researched, CDP choline and bitartrate are better researched. Simple phosphatidyl choline or soy-sourced phosphatidyl serine are the best researched. Incidentally, phosphatidyl serine is a commonly recommended supplement (Bulknut has it).
S
- Plenty of omega 3’s, specifically epa/dha = crucial. Fish oil is generally a better source than flax, however they provide different benefits..

- Diet and esp. Cardiovascular exercise are going to help.

Also: these guys are a bit nutty.. But this is the best forum for research into these topics: http://www.immi … rum/forums.html

****Note: I wouldn’t just start a supplement regimen w/o adequate research. I’d also add 1 supplement at a time if you’re feeling a bit iffy about it. This doesn’t go for say.. Fish oil or P.serine or coq10, but perhaps for some of the other supps.. Many people like to stick to a simpler program (mine isn’t so complex despite what I’ve included in this thread)****

Note2: a psychiatrist may actually help with pharmacological issues (psychiatric drugs.. If you’re a serious case, however, they’ll basically be experimenting with you and creating a soup out of different drugs until they find something that presumably works. I don’t have too much faith in this (I know I seem to be contradicting what I typed earlier.sorry). I don’t think we have the technology to really "fix" our brains.just based on personal experience. I am, however, under the direction of a psychiatrist for now).

I have an account with the MIMS website- it’s like an online dictionary for every medication and can tell you whatever you want to know about it. If you want to know more about a certain drug, just ask and I will post them up :)

Ok, I live in a country with Socialized medicine, but I don’t know what your idea from this is. If somebody goes to the doctor with emotional problems, doctor may take maximum 5 minutes (which is the maximum time allowed per patient by law, doesn’t matter what the disease is) and will prescribe him some drugs. After he’ll give the patient a paper to show in the reception and the guy there will manage him to see the psychiatrist (speciallist). If this guy is lucky he will only need to wait 3-4 months to get assistance (as you can imagine, lists of patients for speciallists are quiet long). It happens with emotional diseases and all others. Here in Spain you have three chances: you go to the urgent department half dead and they give you preference to be assisted, you pay private medicine (which is also fucking expensive) or you have to do it like I’ve just explained.

And if you don’t trust me just ask someone who had bad luck needing Public medical assistance in Spain.

I don’t know what your disease is, but nowadays there are a lot of methods to fight against almost all forms of emotional problems. Drugs can be very helpful in some cases, but they are ALL shit if you don’t follow a spoken therapy. Patients need to talk, need to be listened, need to get strenght for fighting, need to recognize their problems, need to build up strategies to act against certain things, need self confidence, etc. and there is no fucking drug in the world which can give you that. Ok, yes there are a few like MDMA or cocaine, but I don’t think you wanna start with that.

I have personal experience in psychology, I’ve dealt with a lot of people with serious problems and except extreme cases of bipolar disease, schizophrenia, major depression and similar, drugs are only a little help. In 90% of the cases spoken therapy is more important than drugs. And I can tell you something; in my experience I know about two kind of people: people who want to fight and people who want to cry.

If you really think that taking 50 differents supplements will help you to feel good with yourself and happy, do it your way. I wish you good luck.

Do you glow in the dark? Do you cause interference when you walk by a radio?

Are you not afraid that the acidophilus is going to consume all of these substances and mutate into an Alien and come crawling out your chest?

I have been on fish oil longer than anyone here almost. Except for about a six month break, I was continuous from maybe Summer 99. I was prescribed it by my Osteopath for its anti-inflammatory properties with ulcerative colitis. I also have been prescribed Paxil which made me dick go numb by day three for my colitis. Evidently a simple SSRI has a measurable effect for the majority of the afflicted. I was switched out to Zoloft which worked very well, other than a spiking back pain that was very painful and random.

I tried St John’s Wort about 5 years ago for a stint after the Zoloft and felt it was so-so at best. I did double stack with SAM-e & 5htp just to get it to saturate faster. I recall getting drowsy after many weeks of both, till I quit.

I also quit smoking last Thanksgiving 2006. To make it through I found a protocol of herbs, and over the counter stuff to assist like the tyrosine, 5-htp, etc… I followed that and didn’t cheat once.

I picked up an acupuncturist around may of 2007 to work on my colitis. I made very good progress till the beginning of the Fall. She saw how much shit I was taking for the smoking stoppage and weaned me off most of it and added some. That is where I picked up the Turmeric from. She tried to get a psychiatrist for $60 to oversee all my OTC meds and make sure I wasn’t getting all crazy from it. Of course that fell through when the shrinker couldn’t be bothered with for pocket money.

I was without insurance from April 2000 till December 2007. I finally was able to get a personal policy and in the first week of having it, got $4000 worth of blood work looking for why I was so messed up. During this time I had just Turneric, fish oil, and whatever Chinese herbs that were written specifically for me. Anyhow, I was tested for Mono, Lupus, MS, Lyme, diabetes, Hypothyroidism, etc… All my blood work came back as acceptable except for not too far off cholesterol in half the categories.

So far, other than what fatass wrote me with the lexapro, everything has been what can be bought OTC at a drugstore or health food/vitamin shop. No drugs written off script/purpose, nor overseas stuff flown in either.

Nope, but I do have the fucking wickedest gas ever seen or smelt. I can drop a deuce over Hell and destroy everything below like they had peaked into the Ark of the Covenant. When I pass on the throne, even my own eyes water up now. I thought I was immune to my own.

I found that test over at that first link you gave me. I was reading posts over there in which everyone loves to disagree 24/7 with each other. I came across this and will take it and see if it can pinpoint areas instead of my blanket bombing.

I am open-minded but semi-skeptical.

Thanks for your help everyone, if you see an unshaven Deniro impersonating pissed off 7ft white man driving an unregistered 30,000 lb truck and ramming people off the road, it is a mere coincidence, I swear.

Hey big guy, sad to hear that you still can’t get no relief. I have been experimenting with, (some would say abusing), herbals, nootropics, amino acids, etc., etc, for over 20 years now.

As you know I have my own package deal of oddnesses going on. On the plus side I have abilities in the realm of tweaking those things parasympathetic and autonomic in nature that a Yogi would kill and eat a cow for. But to go with that I am exceptionally mutable in nature to say the least. My reaction to all manner of alternative and/or mainstream medications don’t exactly follow the scientific method.

I am currently having a sweet ride with SAM-e. Saw it on sale while shopping at Costco with a friend and wanted to get her to try it. I used NLP 101 and suddenly we were both getting some to compare notes. O:-) I tried it years ago with no response. This time and suddenly I am experiencing the happy joints that chronic arthritis sufferers sometimes report for Glucosamine/Chondroitin/MSM.

Hey TT you better hope Tom Cruise don’t get a hold of you because if he read what you were taking he would surely be jumping up and down on someones couch. I hope you find some kind of relief my friend:)