Caverject Or Trimix

Hi

Just wanted your expert opinions. I am suffering from Diabetic ED. Which is better Caverject or Trimix injections for erections? Tablets do not work for me. Does PRP or shockwave treatments work? Has anybody had pelvic stent done? Please share your experiences. Thank you

Surprised that no one had an any experience with any of the things mentioned in my previous post. Seen most posting p shot and taking trimix but have no experience to share.

I have never tried just Caverject. I have extensive experience with Trimix. From what I understand, Trimix is three compounds, versus the lone ingredient in Caverject. Trimix is generally abetter option, again from what I understand,as it militates pain that often is experienced from just the PGE-1 in Caverject.

There was a recent podcast on the Huberman Lab with Dr Rena Malik that discussed the use of injectables for ED

Would be worth a listen (also on YT if you prefer to watch it)

I use Trimix and have read quite a bit about other’s experience with just PGE-1 (Caverject). I’m using it as a supplement to my PE regimen, not for ED, but I’ve posted a bit about it on my chemical PE thread, if you want to check it out.

Based on the required PGE-1 dose, Trimix is much more potent in that the ingredients are synergistic. People report having to take 10mcg to several hundred mcg of PGE-1 when taken alone, like with Caverject, and the PGE-1 alone seems to require increasing doses over time if used several times a week. I have been using 0.3mcg Trimix daily (as part of my chem PE regimen) with pretty consistent 3-5 hour response for two months with no need to increase my dose for a reasonably predictable reponse.

People report PGE-1 erections are uncomfortable to downright painful. I imagine this is the higher doses used for chemical PE where the target erection time is 3-6 hours, as opposed to a dose for a 30-60 minute sexual session. But even so, Trimix erections, while crazy hard in the corpora cavernosa when otherwise unaroused, are not painful to me. After about 3 hours or so I get ‘tunica fatigue’ and some discomfort, but nothing like what I’ve read about with PGE-1.

Both require a prescription (unless you go gonzo chemist and try to make your own from PGE-1 powder obtained on the internet). Caverject comes pre-made and in standardized doses that are one-time usage. Trimix requires a compound prescription (meaning each of the components can be prescribed in different amounts for a unique blend) and is made by a compounding pharmacy based on the prescription. It will come in a vial with many doses. If you put the vial in the freezer it will lasts a year or more, so you won’t waste any. You can pre-load a week’s worth of syringes and keep them in the refrigerator, as the Trimix is good for about a month in the refrigerator, but the bulk of your Trimix is in the freezer. So it’s way more cost effective with little to no waste.

There are also Bimix and Quadmix options, depending on your needs and responsiveness, so you and your prescriber can play around with different options.

The other modalities you asked about are reported to have some positive outcomes (which I’ve only read about a bit in passing and am no expert), but if I am correct, both are therapeutic for atherosclerotic disease or vascular insufficiency issues, and may be only beneficial if you have arterial stenosis secondary to your diabetes. They might be worth looking into if Trimix doesn’t work.

Good luck and keep us posted.

BTW, I timed out for an edit where I clarified that the 0.3mcg is the PGE-1 component of my Trimix, and I wrote that based on my PGE-1 dose of 0.3mcg in my Trimix, my 10mL vial has over 300 doses. So even if you pay out of pocket for it, it is very inexpensive per dose.

Thank you so much for your views so far. It has increased my knowledge about the products. I will request my doctor for trimix rather than caverject as it is cost effective and causes less pain. Thanks to all again. I will also watch the YouTube video.