PE and aspirin side effects

Aspirin will definitely increase discolouration if you’re prone to it. It happened to me, without a doubt.

Aspirin and all other non-steroidal anti-inflammatory drugs (NSAID’s) affect blood clotting by inhibiting the ability of platelets to gather and clump. A platelet is one of the 2 part clotting mechanism in the body. The initial response to an injury (such as a cut on the skin or a trauma to a blood vessel) is the attraction of platelets to the site. They begin to clump and release substances that attract more platelets (like ants to a picnic). As this occurs, these substances induce a complex multi-step process of enzymes and proteins that ultimately cause the formation of a substance known as fibrin. (BTW, genetic problems in this enzyme cascade can cause diseases such as hemophilia). The fibrin forms a matrix inside the platelet clump, making the clot firm - vous-a-la the bleeding stops. In a blood vessel, one of the substances released by platelets cause the vessel to constrict making it easier for the clot to form and harden, leading to a thrombosed vessel, either on the surface of your skin to stop bleeding or possibly in an unlucky veins on the surface of the penis.

These two mechanisms can be effected by different classes of medications. Lets dispense with inhibiting fibrin first. The drugs heparin (given by vein in hospitals or under the skin by users) and Coumadin (warfarin - the active ingredient of most rat poisons) and the new drug Eliquis (and there are others), all affect the multi-step cascade of proteins leading to fibrin formation. They affect it at different steps and by different means. Doctors give these meds for severe clotting problems, such as thrombosis of the deep veins of the legs which could cause a clot to travel to the lung (pulmonary embolism) - not a good thing. They also give them frequently now for the most frequent heart rhythm disorder - atrial fibrillation. This can prevent the formation of clot in the left atrium which can lead to stroke. Great drugs — VERY DANGEROUS. They are not given willy-nilly. and must be monitored. You don’t want to be on one. They have no known affect on erection and I don’t want to find out personally, thank you very much…

Aspirin on the other hand is a drug that has been around “since antiquity.” It is the product of the bark of willow trees. It was made into teas and other things and it was found to decrease irritation and pain. It was first purified in the late 1890’s by a small drug and dye company named Bayer and they called it aspirin; the rest is history…It was the non-narcotic pain relieving drug of choice and anti-fever medication until the development of Tylenol (acetaminophen) and paracetamol (in Europe) and after 1970’s when it was found to cause Reyes syndrome in kids. It has lots of side effects (bleeding, gastric ulcers, hemorrhagic strokes, profound allergies, just to name a few). I dare say that if it came before the FDA today for approval, they probably would turn it down. That being said, when used properly it is a great drug.

Platelets live for about 28 days. They are made all the time in the bone marrow. Aspirin inhibits platelets permanently - even in small doses. They become “impotent” so to speak. This makes aspirin so important as a prevention of heart attacks. Never fear, even without active platelets, your blood will clot, just not as fast…The other NSAID’s (ibuprofen, naproxen sodium and a host of other prescription NSAID’s) also affect platelets, but only temporarily; generally 24 to 48 hours.

While there are questions as to whether ibuprofen and naproxen sodium (and the others) cause ED, there is no evidence for aspirin affecting erection (bad or good). I personally take 2 adult strength enteric-coated aspirins twice a day for medical reasons and I don’t have ED, thank you very much…

As for the use of the term “blood-thinners”…This is a misnomer. First of all, generally speaking, aspirin is not called a blood thinner. But in reality, as posted above, heparin, Coumadin, Eliquis, etc. do not do anything to the thickness of the blood - they simply stop clotting by inhibiting the complex protein chain leading to clotting.

Pudendum,

Thanks I’m impressed with your knowledge of the subject.

Where does Ginkyo Biloba fit into this?

Regards
Austfred

But way more info than most of us care to know. Sheesh. The end result is that if you take daily aspirin you are more prone to getting a purple cock if you PE……

Captjohn

Maybe yes and maybe no. It depends on how you personally react to the loss of platelets function. Some people bruise badly with 1 baby aspirin a day (81 mg). As I said I take 650 twice a day and don’t bleed much when I cut myself shaving and I don’t bruise my penis (head or shaft) when I do heavy duty PE (and I have on and off for 7 years). It all depends…

Austfred

Ginko also affects the clumping of platelets like aspirin but by a different mechanism. There are rare cases of life threatening bleeding with ginko but the same is true for aspirin. If you see increases in bruising after you start taking it, penis or anywhere else then you might consider discontinuing it and find another memory supplement like phosphatidylserine. Just a suggestion…

Pudendum, Thanks

I take low dose ginkyo to help my EQ and help with my exercise routine. I am aware you should not use it if you are having an operation or serious work at the dentist etc. I consulted a cardiac specialist this year mainly because there is a history of heart problems in part of my family. She said I was fine and to come back in 10 years. She also advised that I take an aspirin twice a week. I usually take one when I take a cialis. Takes care of the mild headache side effect. She was also OK with the ginkyo. I am 67.

I don’t seem to bruise easily

Regards
Austfred

I suffer from ED (diabetic) and have been experimenting with a number of supplements over the years to help generate improved blood flow to the penis. Currently the most effective combination of supplements that help generate a semi (the best I can get without medication or injections) includes a regular aspirin (daily). Ginko Biloba, l-arginine ethyl ester (5 gr), and tongkat ali. I have been taking this stack, or a variation thereof (but always daily aspirin) for a number of years without any negative side effects as mentioned above.

After cutting back on the aspirin and fish oil I stopped bruising and blistering from the BIb Hanger.

I’m back up to 17 pounds with no problems.

I also adjusted the attachment point higher up taking pressure off the glands.

I think it was a culmination of the aspirin,fish oil,Ginkgo,attaching the Bib to low and increasing the weight to 20 pounds that caused the blisters and bruising.

I have been taking baby aspirin and clopidogerel (to restrict clotting around my two new stents.) since April and I bruise extremely easily now, except on my dick.

Granted I’m only jelqing at present, but railing the wife twice a day and raging hard, especially in the morning.

I know people on Coumadin that bruise if you breath on them.

I can’t imagine trying to hang being on powerful thinners like that.They take a little fall and bruise head to toe.

Gentlemen

May I drop in with a little different aspect of taking Aspirin over long time, even in low dosage: acidity risk!

It is evidence based that the risk for stomach bleeding and ulcers is significantly higher for patients taking Aspirin (or better: acetyle salicyle acid, because that’s the active ingredient of Aspirin) over years compared to the control group. This is actually a quite intense discussion for some years already - in MD circles in Germany especially, as Aspirin has been introduced and still is owned by a German company. The anticoagulant effect is well known and proven, so MD’s tend to use it in a let’s say a wee bit less observant way just because it is “old and well proven”.

But the side-effects due the strong acidity are worse than expected. Even patients absorbing sufficient quantities of water seem to develop these problems over time. Pharmaceutical research (and clinical treatment) has (not intentionally, I hope) ignored these side effects but the evidence is pretty obvious and the evidence data get’s better every year since maybe 10 to 12 years. So if there is a possible alternative pharmaceutical treatment in case of need of anticoagulants talk to the MD of your confidence about it.

This is absolutely no statement about Aspirin and PE, just a little medical info to care about.
Just my 2 cents as usual

Richard65

Well, that’s a quite well known phenomenon as Coumarine (brand name usually “Marcoumar” in ol’Europe) is, a little bit like Aspirin, well proven and totally suitable as anticoagulant.
Effects well known, side effects too, but then - bummer: drug to drug interactions! Anyway a part of pharma wisdom often underestimated.

Because what is a bit less known is that Coumarine and… Grapefruit juice do interact strongly! So after the “healthy” glass of grapefruit juice at breakfast in the elder’s home half of the men (the one’s on Coumarine) won’t stop bleeding after having a shave. Sorry if this is a bit harshly expressed but that’s exactly how a clinical pharmacologist I know told me it is… but he sometimes is a bit overly clear as he is teaching nurses and auxiliary staff :-)

And just to cut rumours: no, I’m neither a MD nor a pharmacist. Just a MD’s son and worked a couple of years around pharmacists.

Happy growing and safe gains!

Richard65