I did some reading on ischemia and from what I can gather ischemia is a blockage of blood vessels which in turn causes oxygen deprivation, this in turn causes TGF-B1 levels increase and prostaglandin E1 levels decrease, smooth muscles waste away and collagen is overproduced, causing scarring, loss of elasticity, reduced blood flow to the penis (and erectile dysfunction).
I like to wear a silicone cock ring during the day, by the end of the day my penis has gained quite a good amount of girth. I notice that for the first half of the day my penis becomes slightly colder, then as the swelling occurs the warmth returns. I do not know if I am doing permanent damage to my penis.but from what I have read about blocking the bloodflow to an organ, I may be doing just that. The following is a quote from wikipedia.
“Erectile Dysfunction and Oxygen Deprivation
Erectile dysfunction most commonly occurs when the penis is deprived of oxygen-rich blood. When oxygen levels to the penis are low, an imbalance occurs in two important substances, TGF-B1 and prostaglandin E1:
TGF-B1 levels increase, which trigger production of collagen, a tough protein that forms all types of connective tissue, including scar tissue.
In addition, there is a reduction in prostaglandin E1, a chemical that suppresses collagen production and relaxes the smooth muscles to allow blood flow resulting in an erection.
When TGF-B1 levels increase and prostaglandin E1 levels decrease, smooth muscles waste away and collagen is overproduced, causing scarring, loss of elasticity, and reduced blood flow to the penis. A number of conditions can deprive the penis of oxygen-rich blood.
Blockage of Blood Vessels (Ischemia). The primary cause of oxygen deprivation is ischemia — the blockage of blood vessels. The same conditions that cause blockage in the blood vessels leading to heart problems may also contribute to erectile dysfunction.”
-Hope our dicks don’t all fall off!