More on high dose Vitamin D3, if it were to be done (somewhat) safely..
"When we look closely at the biochemistry, we see that magnesium is required for the conversion of vitamin D to its active form (1, 25-dihydroxyvitamin D). Vitamin D that is taken orally needs to go through this conversion, a process that can deplete magnesium stores. If a person begins to supplement vitamin D but does not have adequate magnesium intake, symptoms of magnesium deficiency can appear. Further investigation revealed that the patient mentioned above had also developed high blood pressure and heart palpitations since taking the vitamin D—symptoms of magnesium depletion."
As for why K2, well: Is Vitamin D Harmful Without Vitamin K?
So with high Vitamin D3, you need K2 and Magnesium and avoid Calcium, get bloods done to check levels, and limit it to 3 months, more growth happens in the first 3 months anyway (if this works as claimed).
Also don’t do it if you have any compromised organs, especially liver or kidney or heart.
See more here:
https://normshe aly.com/d3-k2-a … tation-surgery/
Also if you check out that page, you will see that the observation was made by another doctor, or more correctly by his patients who told a Dr. Prendergast.
So it’s not just 14 people in the study that had this result!
I think the results can be amplified with pumping and p-shot, if this vitamin D3 thing is valid.
Again, not recommending it, it is inherently risky.
Here is an interesting one: https://www.sci encedirect.com/ … 960076018306228
Highlights:
Daily dosing with vitamin D ranged from 5000 IU/day to 50,000 IU/day.
No cases of hypercalcemia observed using these doses of vitamin D for up to 7 years.
The highest 25OHD blood level attained on 10,000 IU/day was 202 ng/ml.
Mean 25OHD levels on 10,000 IU/day were 96 ng/ml and 116 ng/ml in 2 data sets.
A case of asthma and psoriasis were controlled with 25,000 IU/d and 50,000 IU/d.
My comments: Ok, that’s interesting so 7 years of doses up to 50,000IU a day and there were no serious problems,
While there are people who show up sick from excess vitamin D3, they might be a small percentage of people
If this is anything to go by..
Continued:
Vitamin D3 is a secosteroid hormone produced in the skin in amounts estimated up to 25,000 international units (IUs) a day by the action of UVB radiation on 7-dehydrocholesterol.
My comment: Ok, so you can get half that dose from sun exposure alone!
Continued:
During this time, we have admitted over 4700 patients, the vast majority of whom agreed to supplementation with either 5000 or 10,000 IUs/day. Due to disease concerns, a few agreed to larger amounts, ranging from 20,000 to 50,000 IUs/day. There have been no cases of vitamin D3 induced hypercalcemia or any adverse events attributable to vitamin D3 supplementation in any patient.
My comment: This shows rather clearly that vitamin D3 isn’t as dangerous as it is often made out to be, there IS risk yes, but also risk in not having enough!
It finishes up saying "In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe."
Yes, I can find things saying otherwise, but those seem to be isolated cases of people who have trouble for whatever reason, people that might absorb Vitamin D3 more than most, people that might have some mineral imbalance.
Here is a study giving people 60,000IU of D3 for a week, a lot shorter but an even higher dose, it was safe enough to give to them despite having COVID, and it helped them recover: Short term, high-dose vitamin D supplementation for COVID-19 disease: a randomised, placebo-controlled, study (SHADE study) | Postgraduate Medical Journal
Here is another study that had even higher levels of Vitamin D3 and everything was good: Results of daily oral dosing with up to 60,000 international units (iu) of vitamin D3 for 2 to 6 years in 3 adult males - PubMed
Note that these studies were not including K2 or Magnesium which I would STRONGLY recommend for safety.
Here is another, interesting reading: https://www.mayoclinicproceedings.org/article/S0025-6196(15)00244-X/fulltext
It goes on to mention that when 20,000 people supplemented with D, "Dudenkov et al also found that only 1 person with a serum 25(OH)D level of 364 ng/mL had evidence of clinical toxicity, that is, hypercalcemia."
So one person in 20,000, that’s not bad odds.
More: Physicians are now routinely treating patients with 50,000 IU of vitamin D2 as recommended by the Endocrine Society’s practice guidelines.
It’s routine and a guideline!
I think there is still a risk, but that risk is looking manageable.
Some people WILL become toxic taking just D3 at 50,000IU a day for 3 months, maybe not with the K2 and Magnesium and avoiding calcium somewhat, but some might still.
But it is clear that the risk isn’t so high, after 3 months there is just the chance of a slightly high reading of high Vitamin D, but probably nothing actually detrimental for most.
It looks like a potentially manageable risk, not something out of the question, but not something to be done lightly either.