Corticosteroid injection in the ligament

Sorry if that was unclear - language problem.

What I wanted to say (exactly as you are suggesting) was that I doubt that guys will try this (lack of inj. Experience, lack of pharmaceutical supply, and fear of damage. The risk of damage, unfortunately is not minimal but real - especially in the hands of an inexperienced guy (even pe-addicted physicians inexperienced with corticosteroid injection will probably not go ahead and try this).

First, I was a physiologist from 1983-1989, but my field of research was not my dick but pulmonary physiology - at that time.

Second, now, my field of research is indeed the development of my dick with nice progress taking place, but - to tell you the truth - I am getting a little unpatient. Research of dick development, however, is empirical (trial and error) rather then true scientific studies (I opened a thread into this topic but very few were interested in that - so I gave up more or less and am doing the same what most guys are doing in here: concentrate on your own dick and communicate what I am doing with others (input of mods/vets/even newbies always appreciated).

Third, I am not exactly sure what you want to know exactly. We know, that cortisone, injected into a tendon has a tendency to weaken the tendon’s tensile strength. This translates for me into more length gain a the same hang time x weight. An other effect could be partial or complete rupture of the ligament or avulsion from the pubic bone due to collagen damage / tissue necrosis (= tissue death). As I explained before, this would be an undesired effect in the treatment of - let’s say - an athlete with a sport injury. In the case of a pe-addict it would basically result in the same as penis lengthening surgery, which involves dissection of the ligaments. While I have never considered to undergo penile surgery because I really love sex and would hate to damage my dick due to operation complication, I am accepting the risk if complete lig. Failure (=rupture). Because in this case one would obtain the endpoint of the surgery without the risks associated with surgery.

The other issue would be local infection as a side effect of cortisone injection as a result of locally decreased immune response. That could be a disaster. That’s why I am repeating that the injection technique is so important (absolutely sterile). In my clinical work I have performed about 3,000 corticosteroid injections. I am a meticulous worker, these injections were at the central nervous system (spine) with potentially disastrous effects, a risk that I hav to undergo with my patients every day in my clinical work. I never had that type of complication - so I feel relatively comfortable.

Fourofakind - please feel free to ask more specifically if that is not the answer to your question. I will try to ask - however, if you are interested in the molecular or biochemical processes involved - that I would not be able to answer and - truly - this is not something I am interested in in general (btw - this is not something physiologists are interested in general, rather biochemistry people; anyhow, I am practicing clinical radiology and nuclear medicine now - and the focus is on clinical: if it works, it’s ok, if it doesn’t - dump it; just like empirical pe-research).

Let me know your thoughts and/or further questions.

I’m getting a little impatient, lig still hard as steel and very thick, so I made a second injection (after shaving and thorough desinfection) high - close to the bone, midline, 1 skin inj. But distributed the 1 ml in the midline from the insertion point at the bubic bone very few mm down to 1.5 mm (5 inj into the lig).

Did the inj. While hanging 11 pounds sd lying on my back.

No pain. No hematoma.

Hanging continued for 30 minutes after the inj.

Thanks for the update ttt.

You are very welcome firegoat.

What I forgot to mention: I am already back to 18.5 cm, so I really got back what I had lost because of my frenulum tear in no time.

Now let’s find out how the further progress goes.

Good luck TTT!

:subscribes:

It seems pretty straight forward. Here’s something from TTT’s first link:

Here’s how corticosteroid injections suppress the initial events of inflammation and healing:

• They decrease collagenase and prostaglandin formation. Prostoglandins help recruit immune cells to the injured area to clean up the damaged tissue and start the repair process. Prostaglandins also help increase circulation to the injured area.
• They decrease the formation of granulation tissue, which is needed to heal the area.
• They block glucose uptake in the tissues, enhance protein breakdown and decrease new protein synthesis in muscle, skin, bone, connective tissue and lymphoid tissue. Muscle, ligament and tendon tissue is 70 to 90 percent collagen, which is a protein. Corticosteroids are catabolic promoters, which means they are involved in processes that break down tissue.
• They inactivate vitamin D, limiting calcium absorption by the gastrointestinal tract, and increasing the urinary secretion of calcium. Bone also shows a decrease in calcium uptake with cortisone use, ultimately leading to weakness at the fibro-osseous junction.
• They inhibit the release of growth hormone, which further decreases soft tissue and bone repair.
• They can lead to painful tendon and ligament ruptures.
• They compromise tendon and ligament strength, a scary finding considering that many athletes return to the game or the sport shortly after an injection.
• They can predispose a joint to infection.

Hey triple T, what are your thoughts on using a topical hydrocortizone cream on the top side of the penis to weaken the tunica? Have you considered this?

No, I have not.

Corticosteroids weaken the skin as well, unfortunately. This well known effect is called ‘skin atrophy’cand includes thinning of the skin, depigmentation, and teleangiektasias (small, ugly looking dilated blood vessels). All of that, I really don’t want.

Further, a cream applied topically would only partially be absorbed into the body, but would reach the blood stream first and ALL tendons (and all other stuctures, organs etc) via circulation, therefore tissue concentrations (in patricular in the ligs) would be very low.

Thanks for the quotes regarding the effects of corticosteroids hoppefully satisfying fourofakind.

TTT I have been thinking of trying some DMSO along the top of my shaft when doing hanging for its effects on collagen. Did you ever consider that during your research into your ideas you’re trying?

DMSO - is a solvent .. It helps pharmaceuticals to travel through the skin.

Which pharmaceutical do you want to use?

And - whichever you will choose: after travelling through the skin it will be absorbed into the blood before reaching your dick *s*. Therefore, my belief is that topical application is probably useless.

Sorry - dmso has also collagen softening properties, and antiinflammatory effects - but again - it will not arrive in the ligs other than by the circulating blood, and many other effects:

Pharmacology of DMSO

Very interesting - all these properties. But I think it will have to be injected in the ligs as well. Not sure jet if it is at an acceptably low risk though.

Thanks very much for the suggestion.

Other threads covering intralig inj:

Pharmacochemical pe: calcium antagonists - intralig. injection
And
Growth hormone injection into penis base ligament

[QUOTE=ticktickticker]
Sorry - dmso has also collagen softening properties, and antiinflammatory effects - but again - it will not arrive in the ligs other than by the circulating blood, and many other effects:

Pharmacology of DMSO

Very interesting - all these properties. But I think it will have to be injected in the ligs as well. Not sure jet if it is at an acceptably low risk though.

Thanks very much for the suggestion.
[/QUOTE/]

That was kind of my idea, to soften all the tissues in the area so the actual shaft would stretch easier.

[/QUOTE/]
That was kind of my idea, to soften all the tissues in the area so the actual shaft would stretch easier.
[/QUOTE]

Well - that’s what I am trying with my injections into the lig.

Do you have an idea if that can be done safely with dmso? Is it available as a sterile solution for inj.