Originally Posted by BTBassist
Good catch, thanks.Yes, I was ABSOLUTELY thinking about IGF-1 resulting from HGH injections (the HGH has to be processed by the liver, etc. as stated). I apologize. It has been a long few days (hardly any sleep), and it has been awhile since I have dealt directly with HGH and associated peptides.
Pure IGF-1 (or LR3, etc.) will bind without being processed by the liver first (assuming receptors are present in the target tissues). I immediately thought back to a guy who was talking about injecting HGH directly into his penis.
Do remember to keep your dosages low. Whatever is taken up by the receptors is taken up, and what’s left goes to the rest of the body. Keep in mind that your intestines have a high concentration of IGF-1 receptors, so too high of a dosage will likely serve to give you a larger gut. IGF-1 can’t stimulate growth in areas with no IGF-1 receptors, so keep that in mind when/if experimenting.
Good advice here. I’m with you on how you described receptor binding.
I believe there was also an old log on this forum from stagestop (might have been someone else) who was doing IGF-1 straight to the penis. He was doing a considerable dosage, and eventually noticed prostate discomfort. When he lowered his dosage, he was ok. Everyone was pretty convinced it was because his prostate was growing in response to the IGF-1, so I think that it might have something to do with corpus IGF-1 receptors being occupied and then the IGF-1 going and binding to other tissues. Like one that is closeby in the circulatory system, the prostate. That’s speculative, though.
stagestop’s experience goes to show that IGF-1 is a serious matter, though. And like you said, the intestines have lots of IGF-1 receptors. Huge gut growth is well documented in bodybuilders that use a lot of IGF-1 and HGH.
I think that people should only go to IGF-1 after having reasonably exhausted all manual exercises. Even then, PGE-1 is more established as an effective chemical to experiment with.