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Probiotics Affect Metabolism, Says New Study

Probiotics Affect Metabolism, Says New Study

Probiotics Affect Metabolism, Says New Study

ScienceDaily (Jan. 16, 2008) — Probiotics, such as yogurt drinks containing live bacteria, have a tangible effect on the metabolism, according to the results of a new study published January 15 in the journal Molecular Systems Biology.

The research is the first to look in detail at how probiotics change the biochemistry of bugs known as gut microbes, which live in the gut and which play an important part in a person’s metabolic makeup. Different people have different types of gut microbes inside them and abnormalities in some types have recently been linked to diseases such as diabetes and obesity.

For the study, researchers from Imperial College London and Nestlé Research Center, Lausanne, Switzerland, gave two different types of probiotic drink to mice that had been transplanted with human gut microbes. Probiotics contain so-called ‘friendly’ bacteria and there is some evidence to suggest that adding ‘friendly’ bacteria to the gut can help the digestive system.

The researchers compared the levels of different metabolites in the liver, blood, urine, and feces, of mice who had received treatment with probiotics and those that had not.

They found that treatment with probiotics had a whole range of biochemical effects and that these effects differed markedly between the two probiotic strains, Lactobacillus paracasei and Lactobacillus rhamnosus. Adding ‘friendly’ bacteria changed the makeup of the bugs in the gut, not only because this increased the number of such bacteria, but also because the ‘friendly’ bacteria worked with other bacteria in the gut, amplifying their effects.

One of the many biochemical changes observed by the researchers was a change in how mice treated with probiotics metabolised bile acids. These acids are made by the liver and their primary function is to emulsify fats in the upper gut. If probiotics can influence the way in which bile acids are metabolised, this means they could change how much fat the body is able to absorb.

Professor Jeremy Nicholson, corresponding author on the study from the Department of Biomolecular Medicine at Imperial College, explained "Some argue that probiotics can’t change your gut microflora - whilst there are at least a billion bacteria in a pot of yoghurt, there are a hundred trillion in the gut, so you’re just whistling in the wind.

"Our study shows that probiotics can have an effect and they interact with the local ecology and talk to other bacteria. We’re still trying to understand what the changes they bring about might mean, in terms of overall health, but we have established that introducing ‘friendly’ bacteria can change the dynamics of the whole population of microbes in the gut," he said.

The researchers hope their new insights about how probiotics and gut microbes interact will ultimately enable the development of new probiotic therapies, which can be tailored for people with different conditions and different metabolic makeups.

Dr. Sunil Kochhar, another author on the study from the Nestlé Research Center, added: "Understanding changes in the molecular events triggered by the so-called beneficial bacteria in the host metabolism is an important prerequisite in our efforts to develop customized nutritional solutions to maintain and/or enhance our consumer’s health and wellness at an individual level. The results of this study are highly promising to address personalized nutrition."

Adapted from materials provided by Imperial College London.

Probiotics Affect Metabolism, Says New Study — ScienceDaily


“You see, I don’t want to do good things, I want to do great things.” ~Alexander Joseph Luthor

I know Lewd Ferrigno personally.

So from what I infer, probiotics increases metabolism?

Important parts are the one about the bile acid and fats.


“You see, I don’t want to do good things, I want to do great things.” ~Alexander Joseph Luthor

I know Lewd Ferrigno personally.

Stock up the vitagen!!! I’m gonna increase my metabolism and loose weight!!!

I take massive doese of probiotics and I barely lose a pound. of course, I did test negative for hypothyroidism, but maybe my ulcerative colitis makes it not work as good?


“You see, I don’t want to do good things, I want to do great things.” ~Alexander Joseph Luthor

I know Lewd Ferrigno personally.

My wife has ulcerative colitis as well. She’s had years and years of digestive issue and was finally diagnosed with it last year. Right now her Aloe Vera extract pills seem to be doing the trick.

That may change in a few months. Hopefully not.


If girth is king, why the hell does everyone keep talking about length?

10 years with mine as of Christmas Day.


“You see, I don’t want to do good things, I want to do great things.” ~Alexander Joseph Luthor

I know Lewd Ferrigno personally.

What do you do to control/manage it?


If girth is king, why the hell does everyone keep talking about length?

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