Blueray, high dose zinc can raise both testosterone and free testosterone. Need a lot more then 30mg of whatever to do that. If your moderately deficient than 30mg may bring one back to normal. You are correct about zinc supplements. 50 mg of zinc gluconate does not contain 50 mg of elemental zinc. More like a couple of milligrams. I don’t have the exact amounts in front of me at the moment. So one would have to take many, many pills to get 100mg of pure zinc.
Yes gluconate and sulfate (the one most doctors and studies use is the sulfate version) can cause one to have an upset stomach and some even throw up from it. Taking with food does usually prevent this. In fact in some studies the zinc was taken with a glass of milk. And I bet many here have read calcium interferes with zinc absorption. I’m sure it does but maybe not as bad as is thought? Calcium competes more heavily with magnesium.
Yes there is at least one study that correlates 100mg of zinc with prostate cancer. It also can effect the urinary track causing pee problems.
Yes to much zinc can accelerate hair loss just as to little zinc can.
Yes zinc can cause headaches.
The main zinc concern is it’s possible effect on copper depletion. It my compete with copper. If you have copper plumbing pipes in your house your probably getting plenty of copper if you drink your water. If you take a multi your probably getting plenty of copper. I would not worry about to little copper unless your actually taking 100+ mg of pure zinc every day for an extended length of time. One has to make up their own minds concerning all of this stuff.
It is doubtful one would take enough pure zinc to (acute dose) to wind up in the E.R. Chronic use may do that? I would cycle high doses if I decide to use it that way. I would not worry about dying from taking a couple of 100 milligram zinc gluconate pills. Again, it’s like maybe 20 mg of actual zinc. I would expect to feel sick and maybe throw up. I would also advise spreading doses through out the day. To avoid feeling sick.
Have fun. Play safe. Research every recommendation. Make your own informed choice.