CRISPR-CAS9 and penis DNA enlargement.

We need the smart guys of the form who have PhD’s in bio/chem/genetics to look into this.

From the writing style in some of the chemical PE posts, I can tell there are some very intelligent members.

I personally believe that there is a genetic limit to how much you can gain based on what you’re starting with. Every guy can gain, yes. But, I believe that one’s DNA will set a limit on how much they can enlarge their penis. [ extreme example: if some guy starts with 3 inches, and is trying to get to 12 inches, I’d assume a serious injury would occur before they got to 9 inches. Maybe an obvious statement?]

So, this is me formally asking someone to pls look into this. <3

We need the smart guys of the forum***
(typo)

No serious person would go that far for anything for you’ll never know the outcome nor the long term consequences. Like there really was there a crispr technique that does the job and the job only. It always ends up a mess. There is no such a thing as crispr treatments nor mrna gene therapy which are known to be successful in any manner.

Pretty terrible argument.
People break their dicks from jelqing/clamping all the time.
Pretty sure Crispr-cas9 will have less risks + side effects when the technology is perfected.

I agree, I’m a bit surprised with the argument made by Redmorsilla since manual PE methods aren’t without significant risks; I talk to Urologists and other Penis-related Physicians all the time (due to my role on the PhalloBoards) and it isn’t uncommon to hear about the damage they see from men who perform these exercises.

I’m convinced advancements in genetics will be the future of penis enlargement, but I think it will be quite some time till we see those kinds of developments. Currently, most (if not all) Research & Development funds are going to be allocated toward life-saving studies; cosmetic enhancement is so far down the list of priorities to Academics & Scientists that we’d be lucky to see successfully implantable lab-made penises in our lifetime. That said, organs are being made in labs, and while they might not be “100% successful” in the eyes of some, the logical conclusion is that someday they will be. By extension (no pun intended), this will eventually yield limbs & extremities. Deformities and trauma-patients will likely get first dibs, then the very rich, and then perhaps the rest of us one day.

The immediate dismissal of technologies showing promise in labs is precisely why some of us will continue to break our dicks through less refined techniques. I mean heck, I personally believe advancements made in male phalloplasty are already considerably more effective than manual methods of today, and those advancements were made through scientific/medical means. Of course nothing is without risk, but this topic of biogenetic enhancement is an inevitability, why not talk about it?

^ basically this guy(Josiah zayner) injected himself with some suspension with using CRISPR-CAS9 in 2017 that was a myostatin inhibitor to increase muscle gains. He never lifted weights so he never made gains. Currently, he has become a transwoman (please be respectful to his decision).

However, doing something similar may be the first step with CRISPR-CAS9 for penis enlargement. Likely, you’ll still need to train the penis. But perhaps turning certain genes (there is myostatin in the penis so maybe the myostatin inhibitor CRISPR-CAS9 suspension used by Zayner?) would allow for faster growth *if you were to continue penis training*.

I think CRISPR-CAS9 may be of use to change your DNA to allow for a higher baseline of potential gains, so that you can do less risky techniques, say lighter pumping sessions opposed to more intense clamping + over engorgement methods. A lot of people say clamping works better than pumping, but the injury risk is much higher with clamping than pumping.

Also, thoughts on
1.growing androgen receptors from stem cells then injecting the lab grown androgen receptors into the penis? (goal whould be for a hormone like dihydrogentestosterone (DHT) to make the penis grow similar to how it grows during puberty)
2. Growing penis tissue in a petri dish then putting the cells into the penis?

Because I’ve had some experience in fitness, my mind jumps to method 1 being more fun (and more practical?) than method 2.

My only concern here is medical self-experimentation, especially if the person performing on one’s self isn’t qualified through extensive study and/or experience.

This is why I believed this would be an inevitability much further down the road. If someone were somehow successful all on their own, I doubt it would gain any traction because it would probably involve a lot of “know-how” on the part of the individual, and medical circles would likely dismiss it as pseudo-science (and this is under the assumption that any success is even achieved, and that this success isn’t anomalous/lucky).

If someone is this eager to achieve gains (by circumventing or supplementing manual PE exercise), then I think modern male phalloplasty offers less risks overall. You can even argue that the use of dermal fillers for girth enhancement is a sort-of “biohack” and demonstrably effective, unlike the speculative nature of self-experimentation.

That all said, this remains an interesting topic, I’m just not sure I personally would advise or advocate for performing any injections on one’s self without medical supervision.

From what you’ve exposed, it’s clear you guys are not fully aware of what crispr is or what are it’s potential uses.

You could work out Crio-editing to achieve such feat as a larger penis. But you’ll need a few bits and pieces of actual crio-big dicks. But you’ll actually have to know if that source embryo will actually have a big dick when full grown, so you must harvest tonnes of samples and then wait 20 years to see if they did actually grow a large dick and only then be able to use thise embryo-dick parts in an actual embryo and it will become a well hung adult. Similar things are done with race/polo/jump horses. As well as with cattle, but are not permitted to perform on humans because of several laws on the subject.

Even the guy in china who did crispr to the twin girls to supposedly give them resistance to hiv, was taken away by the CCP never to be seen again. That experiment resulted in a mess, btw.

The enriched cell injections tend to be reabsorbed by the body. Same goes with fat transfers. But, there might be some hope to mother-cell cultures, thing is first you need to discover what hormones are sparking them to become penis structure and not just fat cell (and end up reabsorbed).

I assume you were talking to the only two others in this discussion, except I wasn’t making a case for crispr with respect to penis enlargement. Instead I iterated my optimism that advancements in genetics (which is quite broad) could yield solutions in male enhancement some day. Given today’s trends in both science & medicine, it isn’t as nearly as farfetched as it might have been decades ago.

On a side note, while I can’t say I’m well-versed in CRISPR-CAS9, much of what I have read appears to be promising, or at the very least, indicates a significant degree of advancement in the field of genetics, and this in it of itself should be considered promising (regardless of any current success or failures).

While I can’t seem to corroborate your claims about the CCP taking away twins because of some sinister “fill-in-the-blank-nonsense”, their story in no way invalidates the potential benefits of this type of gene therapy; however, it definitely raises ethical questions for completely different reasons.

I’m not sure I follow? I assume you’re chiming in on my comments regarding modern male phalloplasty? I use the term “modern” mostly to indicate how far things have come along.

There are methods that aren’t permanent, yes, but are still effective in providing size, and some men retain their size for as many as a few years. Then there are also permanent options, some of which have also proven to be successful.

I’ve followed the cases of thousands of men for over 10 years through progress-reporting-level information, and I can tell you that some (not all) of these methods are worth considering if you’re a hard-gainer or notably under-average.

I’ve gained nearly 3 inches in erect circumference through the aforementioned “bio-hacks”, and have had it in my penis for over 10+ years with no complication.

So if it was male phalloplasty you were talking about, don’t be so quick to pass judgment ;-)

I recall reading somewhere that a major factor in penis size is genetic variation of the testosterone receptors.
Something about having a longer chain of a certain amino acid on the end of the surface protein correlates strongly with smaller penis size.

Which makes some sense. It doesn’t matter how much testosterone one makes as much as how well it binds to specific receptors.