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Completely agree. A topical lotion could be interesting but not worth getting an aneurism.
More than anything, to me, this study scientifically proves that softening the tunica and pumping works really well for PE.
In the past people have said there is no scientific evidence for PE and it’s not possible. We know they are wrong but it’s good to have science backing you up.
Completely agree. A topical lotion could be interesting but not worth getting an aneurism.
More than anything, to me, this study scientifically proves that softening the tunica and pumping works really well for PE.
In the past people have said there is no scientific evidence for PE and it’s not possible. We know they are wrong but it’s good to have science backing you up.
I was looking into the topical lotion with anti-LOX, and I found out something interesting about Pyridinoline (the cross-linking compound of collagen fibers). It is found in the collagen of bone and cartilage, as assumed, but not in skin. Also, it is NOT present in newly synthesized collagen, and is formed from aldamine cross-links during the maturation of collagen.
So, I suppose we want to stimulate “new” collagen and it will be very stretchy, until it matures.
So, I suppose we want to stimulate “new” collagen and it will be very stretchy, until it matures.
I think you just nailed it.
START 18/13.15 cm Jul 24th 18 (7.09/5.18") NOW 22.5/15.2 cm Fer 12th 20 (8.86/5.98") GOAL 8.5"/ 6"
When connective tissue is stretched within therapeutic temperatures ranging 102 to 110 F (38.9- 43.3 C), the amount of structural weakening produced by a given amount of tissue elongation varies inversely with the temperature. This is apparently related to the progressive increase in the viscous flow properties of the collagenous tissue when it is heated. (Warren et al (1971,1976)
This is from a scientific journal article titled, "A simple practice guide for dose conversion between animals and humans." One way to calculate Human Equivalent Dose (HED) is:HED (mg/kg)= [Animal NOAEL (mg/kg)] × [Weight animal (kg) / Weight human (kg)] ^ 0.33
NOAEL is the no observed adverse effects level.
The reference weights are in Table 1 in the study, here is a link:So if we assume that the 100 mg/kg is the NOAEL, the HED is then 13.8 mg/kg per day. The article says to add a factor of safety of 10, so its 1.38 mg/kg for the first human trials.
And the cost is $50 per 100 mg; then the price for a 90 kg man is $62.30 per day.
Is the antibody out of the question now? I’m still curious how to use this information.
62.30 are you sure? Its reasonable price
The cost of the chemical compound mentioned in the article is 10 dollar per mg. So 100mg would be at 1000 dollars. And that is assuming that the producing lab sells to public.
inicial 1996: BPEL 15cm (Margin of error +/- 0.5cm) MSEG: 14.1 cm
inicio extender (sept2012): 15,5cm BPEL /14,1cm MSEG --- Hanging: inicio: Ago 21 2022 21.0cm --- Ultima medicion: Sept 1 2022: 21.6cm BPEL x 15,1cm MSEG
Meta: 28cm BPEL x 21cm MSEG -- si, quiero tenerla mas gorda que tu vieja. jaja