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Scientific evidence for PE!

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Completely agree. A topical lotion could be interesting but not worth getting an aneurism.

More than anything, to me, this study scientifically proves that softening the tunica and pumping works really well for PE.

In the past people have said there is no scientific evidence for PE and it’s not possible. We know they are wrong but it’s good to have science backing you up.

Interesting Fact about Pyridinoline

Originally Posted by Nudgetracker
Completely agree. A topical lotion could be interesting but not worth getting an aneurism.
More than anything, to me, this study scientifically proves that softening the tunica and pumping works really well for PE.
In the past people have said there is no scientific evidence for PE and it’s not possible. We know they are wrong but it’s good to have science backing you up.

I was looking into the topical lotion with anti-LOX, and I found out something interesting about Pyridinoline (the cross-linking compound of collagen fibers). It is found in the collagen of bone and cartilage, as assumed, but not in skin. Also, it is NOT present in newly synthesized collagen, and is formed from aldamine cross-links during the maturation of collagen.

So, I suppose we want to stimulate “new” collagen and it will be very stretchy, until it matures.

Originally Posted by Alex2.0

So, I suppose we want to stimulate “new” collagen and it will be very stretchy, until it matures.

I think you just nailed it.


START 18/13.15 cm Jul 24th 18 (7.09/5.18") NOW 22.5/15.2 cm Fer 12th 20 (8.86/5.98") GOAL 8.5"/ 6"

When connective tissue is stretched within therapeutic temperatures ranging 102 to 110 F (38.9- 43.3 C), the amount of structural weakening produced by a given amount of tissue elongation varies inversely with the temperature. This is apparently related to the progressive increase in the viscous flow properties of the collagenous tissue when it is heated. (Warren et al (1971,1976)

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