How to GROW the penis with growth factors?

Ok, so this is a developing (pun not intended) subject.

So, it is somewhat well know that Testosterone grows the Penis, but that the window in which this is true is mostly limited to puberty except for men who were under-exposed to Testosterone in youth, but then the growth they get as adults from supplemental Testosterone is limited.

Ok, so is that the end of it? Well, maybe not!

Other body tissues grow just fine without exposure to Testosterone!
There are numerous growth factors, and there is evidence that maybe they can grow the Penis.
There are a few bodybuilders who have taken HGH in very large amounts and had basically everything grow including their penis.
And there are PRP injections into the penis which when combined with pumping seem to be able to great more marked increase in length and girth than would be expected from pumping alone.

So, is that it? Well, there is also the Vitamin D study which showed that megadoses of Vitamin D3 can create penis growth, well not only does Vit D increase Testosterone, but it also increases IGF-1 (Insulin like Grorth Factor 1).
So those results could be down to an increase of growth factors, Testosterone and the fact that Vit D is a hormone itself.

Testosterone increases insulin-like growth factor-1 and insulin-like growth factor-binding protein - PubMed <Testosterone increases IGF-1
Vitamin D increases circulating IGF1 in adults: potential implication for the treatment of GH deficiency in: European Journal of Endocrinology Volume 169 Issue 6 (2013) <Testosterone significantly increases IGF-1

So, what can IGF-1 do? Note, there are many many growth factors, IGF-1 is just, well one of them.
"Growth hormone stimulates many tissues, particularly the liver, to synthesize and secrete IGF-1, which in turn stimulates both hypertrophy (increase in cell size) and hyperplasia (increase in cell number) of most tissues, including bone."
According to the Encyclopedia Britanica.

So it literally increases the number and size of cells of MOST tissues, even bone.ers? Boners?

"But why wouldn’t every body builder report this"?
Well first some do, but bodybuilders aren’t likely doing PE exercises, they take Testosterone that shuts down their natural production and likely leave the Penis less to work with, but more-over both the IGF-1 and other growth factors and hormones they take are literally USED UP by the muscles they grow and break down. The exercises and muscle breakdown and growth literally uses up these factors leaving not much for Penis growth!
Or, that’s a reasonable theory.

Ok, so if this is true that growth factors are a key to penis enlargement (especially when repair is triggered through pumping, stretching etc) then how would we increase IGF-1 and HGH and the like?
Note, HGH apparently increases IGF-1 also.

Well, no doubt this list will grow (and you could just buy IGF-1 and inject it into the penis directly, albeit you will need to obtain it illegally) but here is a list of ways to increase IGF-1

D3 - Take it with K2 and Magnesium, and if doing the rest of this you might not need to megadose it quite so high, D3 increases IGF, maybe after it increases T.
Bromelain - Increases Testosterone and destroys fibrin (scar tissue), T. Increases IGF-1 so likely it increases IGF-1 also.
Melatonin - Increases IGF-1 through release of HGH.
High protein diet increases IGF-1
Intermittent Fasting increases IGF1
High protein diets and low carbs both increase IGF-1
High Impact interval Training increases IGF-1
Zinc significantly increases IGF-1 (and Testosterone)
GABA increases IGF-1
Beta alanine IGF-1
Magnesium increases IGF-1
Zinc increases IGF-1
Selenium increases IGF-1

Of course, you can find articles on increasing IGF-1such as this one which I haven’t gone through fully.

BTW on the subject of the growth factors in PRP, according to a medical presentation from a doctor to other doctors, here are the number of proteins and growth factors in PRP:
Over 30 bioactive proteins
7-12 growth factors.

IGF-1 (and other growth factors and hormones) doesn’t need to grow the penis in the same way Testosterone does in puberty, it just needs to work the same way body builders grow tissues by breaking them down while high levels are present either systemically or injected or topically applied to the penis!

There is no reason to think that when non-muscle materials are broken down and attract healing under the influence of tension/elongation that growth factors wouldn’t help because they remain a key to healing after all!

Dudes, do you realize how big this may be in the area of penis enhancement?
This might lead to a real version of the pill that (with a little pumping, ADS, Jelqing) leads to real and relatively dramatic growth!
Or, a topical presentation, or injection..

Sure, it is as yet a theory, but there are no massive leaps here.
It is entirely reasonable, and there are ways to try it that do not require borderline irresponsible doses of D3 or injections into your wang or obtaining prescription substances illegally.

TLDR Penis Enhancement works by injuring and stretching the penis and letting it heal in an elongated state, therefore if something is responsible for healing, cell elongation and multiplication it would help, and IGF-1 does just that!

Bodybuilders take Testosterone, HGH, IGF-1 and various other performance boosting and illegal substances and then their muscles just pile on without doing anything as they sit around watching netflix right?

NO! Bodybuilders take those growth enhancing substances and then they damage their muscle fibers, the body sends growth factors, amino acids and more to heal and make their muscles stronger and bigger only once damage has been done.

So, is this something special about muscle fibers?
I would argue that obviously no! Not at all!
Actually, I don’t need to argue that, it has already been established that these growth factors heal all such tissues including penile.

The ONLY thing that makes this especially true of muscle fibers is how easily they are damaged!
But it is just as true growth factors at least (if not Testosterone directly) obviously can help heal and grow all forms of human tissue as I quoted from the Encyclopedia Britannica!

So there really shouldn’t be any doubt that something that makes a marked increase in IGF-1 has the potential to grow the Penis when the following is true.

1, there is a Penis
2, the penis is undergoing repair from stress/strain and microtears and ideally remains in an elongated state.
3, there isn’t an overwhelmingly greater demand for the IGF-1 elsewhere (it’s not used up by work-outs).

Note, if the growth factors are implanted directly into the penis it might not matter if there is need for repair elsewhere, but if the increase is systemic then exercise that fatigues muscles wouldn’t be that helpful.
BTW SIT/HIIT increases growth factors and then they decrease, in other words it triggers their release but exhausts the supply, but the less you damage your muscles from these high exertion exercises likely the more is left for other uses.

While I accept that this has yet to be proven, there really is no obvious flaw in the line of reasoning, really it is obvious that this almost certainly is true and it is just a question of how hard it is to get these growth factors in the right place and induce the right level of micro-damage.

Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: evaluation of loaded and unloaded ligaments - PMC
Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: evaluation of loaded and unloaded ligaments

Doesn’t that sound like it pretty much describes the penis "collagenous extracellular matrice"?

The only thing that could really be called an assumption is that something advertised to help multiplication and elongation of cells would be helpful not just healing but leading to a larger member..
And as far as jumps of logic go, they don’t get any smaller!

IGF-1 -HAS- to help heal the penis of that there is no question, the only question is if that help would lead to faster penis growth when the penis is being grown through mechanical means and that seems like the safest conclusion possible even if the results of the P-shot, VitD3 study and reports from body builders didn’t exist or couldn’t be explained though this mechanism.
It could very well be that hardgainers have low IGF-1 or IGF-1 (and other GH’s) are being used up by some other activity or illness!

Ill save this page, thanks bro.

Interesting read.

Could HGH peptides (Ipamorelin/Sermorelin) have the same effect as IGF-1?

Penislongerer, you had mentioned a few things in another thread. I asked you some questions about them but apparently you didn’t see ‘em. They were, why would NZ customs block the import of the D3 you ordered? Wouldn’t mega-doses of Melatonin make you very tired? And what is a PRP shot?

Didn’t see your reply..

NZ Customs have a silly rule about D3, not even totally sure what it currently is but I have had higher dose (10,000IU) blocked at customs before.
They also have a silly rule about Melatonin but I managed to get that in the other day.
They also have a silly rule about DHEA, and Yohimbe. Incidentally I ordered some of piping rocks super horny goat weed complex and only after ordering realized the Yohimbe might cause it to be stopped, and the other package has large doses of D3, so we will see if my luck hold out.

Basically they take an overly cautious view on some of these things and their take on Vitamin D3 is really extreme.

Megadoses of Melatonin might make me tired, I’d only take it when I was going to bed or woke up in the night and want to get back to sleep, though when I did try it I didn’t notice huge effects.

The PRP shot is blood taken from yourself that is spun in a centrifuge and the red blood cells being the heaviest sink to the bottom, the top portion is platelet poor Plasma below that is platelet rich plasma and then between the red blood cells and the plasma is a thin layer of white blood cells called the “buffy coat”.

The top layer (all the plasma) and some of the white blood cells that can be taken without sucking up RBC’s are suctioned into a syringe and then spun again (well, there are some who only do it once) and then the top layer of platelet poor plasma is sucked off the top and either discarded or used for something else (it isn’t without it’s usefulness) and then the bit at the bottom that is Platlet Rich Plasma is injected into the corpus cavernosum (both sides) and into the glans, and for Peyronie’s (a bend in the penis) into the tunica (intratunical injection) which I assume means not through into the cavernosa but rather into the sheath around the penis.

At any rate this concentration of fractionalized blood products is a storehouse of growth hormones/factors, peptides, proteins etc..
Over 30 bioactive proteins
7-12 growth factors

PRP injections help all sorts of things, joint problems, restore hair growth and they improve erection quality and with pumping have been shown to grow the penis!

PRP is basically a free supply of fresh personalized natural growth factors, you have as much as blood you can afford to lose (the red blood cell component of).

BTW many men have unrecognized iron overload! Hemochromatosis!
Women naturally bleed and lose red blood cells, but men don’t often suffer blood loss events (can’t even remember the last time some one stuck me way a knife in battle, I must be good!).
And we eat more red meat.

I had been intentionally donating blood, but I will give that a miss for a while as I’ll be dumping my RBC’s and re-injecting the rest.

Very interesting stuff. Didn’t you say NZ was actually putting D3 into food products to supplement it? But then they’ll block it at customs? How bizarre is that? Seems like they don’t know whether they’re coming or going. Why it sounds like your government is being run by our libs over here. Control freaks.

I find it interesting that large doses of Melatonin has been found to increase HGH. Indicative of the importance of (albeit elusive) good sleep yes? That PRP shot interesting as well. Kinda sounds like a poor man’s stem cell treatment.