Horny Goat Weed + Coffee - Bad for PE?

Good day gentlemen. I’ll try to keep this brief. I was about to take my HGW this morning with a glass of water when I had a random thought.

Keep in mind, I’ve been taking this stuff (off and on) for a year now. I’ve seen no erect gains in that time period, only temporary expansion girth-wise. Amazing EQ, but no gains. Admittedly, I’ve only been PEing *consistently* for 3-6 months of this past year.

The thought was: What if HGW is like other compounds that I’ve read about which provide anti-angiogenic properties? Well all I did was search epimedium (HGW) and blood vessel growth and boom! It sure enough it does! I pulled this straight from an ncbi article I found. “The anti-angiogenic effect appears to be moderated by down-regulation of vascular endothelial growth factor (VEGF), a crucial growth factor that acts as the fundamental regulator of angiogenesis (Figure ​(Figure4).4).”

I feel like this is bad news for PE if tissue growth is our ultimate goal. Then, as my coffee got done brewing, I got to thinking… what about coffee.. quick google search.. same thing! Now I’ve been a religious coffee drinker for over ten years. But the data is clear that there are several compounds in coffee that, like HGW, are clearly anti-angiogenic. This is great for cancer of course, but I’m so sure about PE. I was going to attach graphs from both articles but I feel there is no need as the info is readily available.

I can tell you right now, there’s no way I would give up coffee for PE, not completely. HGW, sure, but not coffee. Anyone else have any thoughts on this? Any long term coffee drinkers and/or HGW takers seeing permanent or long term gains?

I’ve always been a heavy coffee drinker.

Nice, there’s one that proves coffee is OK. That’s encouraging, haha.

I can’t say I’m surprised, as I made plenty of gains bodybuilding-wise, while being a heavy coffee drinker. If you can grow skeletal muscle while consuming coffee and caffeine, it’s clearly a good sign. I just know penile tissue is a different ballgame.

I just read another research article about coffee stating that not only was myostatin expression attenuated, but IGF-1 was also up-regulated, resulting in significant skeletal muscle hypertrophy in mice. Very interesting stuff. It seems the anti-angiogenic properties of coffee are far outweighed by other properties. I’ll link the study.

Coffee consumption promotes skeletal muscle hypertrophy and myoblast differentiation - PubMed

So your saying horny goat weed limits PE growth? I take about 2 HGW pills every day or every other day.

Well that’s the question, I’m unsure Rafa. It certainly has properties that prevent new blood vessel formation (anti-angiogenic). Is that effect outweighed by its other blood flow promoting, blood vessel dilating, and smooth muscle relaxing properties? (That’s not including the favorably hormonal response from HGW either.)

In the case of coffee, which also has anti-angiogenic properties, we have at least one person saying they acquired permanent gains while regularly consuming it. I also found several studies that show coffee has anabolic effects on skeletal muscle in terms of myostatin inhibition and increased IGF-1 expression. These should be good things for PE.

Given that coffee consumption is pretty normal, I have a feeling that there are plenty of other guys who are heavy coffee drinkers that have gained. HGW consumption is not so common. So, I’m not as concerned about the effects of coffee intake vs HGW. I really would like to hear from any others if they have gained anything permanent while consuming HGW, (or coffee) so that we can discern if it’s good, bad, or neutral for PE.

I’m taking one horny goat weed pill per day and have no side effects. I have no limits on the amount of coffee. My daily coffee consumption is about 700 ml. So coffee has a more negligible impact on preventing new blood vessel formation. But I’m not sure about a mix of coffee and Advil . My doctor told me that such a ligament provides much better pain relief, but is it has anti-angiogenic properties? Over time, I increased the dose as my body developed a tolerance. So will I have problems mixing HGW with coffee and a 2x dose of painkiller?

Chemicals in horny goat weed may assist enhance blood flow and improve sexual performance. It also contains phytoestrogens, which are molecules that function similarly to estrogen in women. This could help postmenopausal people prevent bone loss. People use horny goat weed for erectile dysfunction and poor sexual desire, weak and brittle bones, health problems after menopause, and joint discomfort. However, scientific evidence for any of these claims is inadequate. So just order some pipes from (deleted spam) smoke weed for pleasure, and don’t expect it to help with your health issues.