Could the study of snake venom benefit controlled penis tissue deformation
There is no way to find out by just reading this, but I’ve heard a lot about snake venom deforming tissues after exposure, now I’m not saying that you should just take some venom and the penis will get bigger. But what I’m suggesting that further studies of snake venom and the reactions of tissue under controlled environments might lead the way to understand the benefits of tissue deformation without death. There is an antidote for the snake venom if bitten in the wild, it uses a plant of some kind which acts alone in some cases and target the venom in the nervous system rendering the venom useless as it deforms the cells.
Could a controlled dose of venom mixed with another tissue isolating chemical change the size of cells in the penis? Could such a thing be possible? It’s a long shot so don’t all laugh at once, but it’s the ideas that people have that spark discovery.
Here is some facts on what people are trying.
The relationship between microstructural features and macroscopic mechanical properties of engineered tissues was investigated in pure and mixed composite scaffolds consisting of collagen Type I and fibrin proteins containing embedded smooth muscle cells.
In order to vary the matrix microstructure, fibrin polymerization in mixed constructs was initiated using either the blood-derived enzyme thrombin or the snake venom-derived enzyme ancrod, each at low and high concentrations. Microstructural features of the matrix were quantified by analysis of high resolution scanning electron micrographs. Mechanical properties of the scaffolds were assessed by uniaxial tensile testing as well as creep testing. Viscoelastic parameters were determined by fitting creep data to Burger’s four-parameter model.
Oscillatory dynamic mechanical testing was used to determine the storage modulus, loss modulus, and phase shift of each matrix type. Mixed composite scaffolds exhibited improved tensile stiffness and strength, relative to pure collagen matrices, as well as decreased deformation and slower relaxation in creep tests.
Storage and loss moduli were increased in mixed composites compared with pure collagen, while phase shift was reduced. A correlation analysis showed that the number of fiber bundles per unit volume was positively correlated with matrix modulus, strength, and dynamic moduli, though this parameter was negatively correlated with phase shift. Fiber diameter also was negatively correlated with scaffold strength. This study demonstrates how microstructural features can be related to the mechanical function of protein matrices and provides insight into structure-function relationships in such materials.
This information can be used to identify and promote desirable microstructural features when designing biomaterials and engineered tissues.
Start 6.5 bpel 5.75 eg Current bpel 7.0 eg 6.75 (7.0eg base) Goal bpel 7.25 eg 7.0 mid shaft
