Remek
Thanks for the warm welcome and help! This site is truly fantastic. The quality of guys here is amazing. I really appreciate such an awesome resource.
Wow, you have some really great posts. I was reading back through some of your earlier stuff. Truly a pioneer and a thinker!!
First, thanks for the posting instructions, but what I meant to ask was how to post a quote from someone else. I think it’s a VB or HTML tag but I can’t find anything on the syntax. So keeping that in mind I will try to cut a paste parts for now.
Quote by remek:
I like this line of thinking.. Iguana, are you aware that the penis consists of 50 percent smooth muscle? I wrote an article/thread on smooth muscle a few months ago; it might help you with your research: The Penis (smooth) Muscle Theory. I could be wrong, but from what I have researched, smooth muscle regenerates too.
Response:
No, I was not aware of this until I had read the Smooth Muscle Theory thread (several times.) Great information! I have to agree with you on the regeneration. I read an article on the regeneration of smooth muscles in pigs (ureter) which has an interesting point. It seems that in this particular case, the regenerated muscle tissues were interwoven with collagen fibers. It states "The regenerated smooth-muscle bundles were oriented in different directions and intermingled with fibrous tissue." May have significance?
Here’s the link, let me know your thoughts please.
http://cat.inis t.fr/?aModele=a … cpsidt=16430689
Quote by remek:
So, let’s assume — for a moment — that we are regenerating the ever-so-needed smooth muscle cells in our penis, then what?
Response:
The statement of your doctor friend makes a lot of sense in that it doesn’t appear we are gaining from or only from scar tissue. This above article also states "By 3 months, smooth-muscle bundles bridged the defect, and by 5 months, the whole defect was covered. Smooth muscle cells were evident by electron microscopy by 3months, and actin and myosin could be detected by immunohistochemistry. Desmin-positive cells accounted for 50% of the population at 3 months and 40% at 5 months." So it appears that, of the added repair tissue, smooth muscle accounted from 50% at 3 months to 40% at 5 months. If this is typical in the smooth muscle repair process could it be we are adding 40-50% new muscle tissue and 50-60% connective tissue? Thoughts??
Quote by remek:
Modesto, I believe we discussed that we’re probably not just exercising one part of our penis, rather many different parts — and maybe even each part is being exercised/enlarged at different rates. Particularly, the smooth muscle could enlarge at one rate, while the tunica could enlarge at another. So after we regenerate more smooth muscle cells, perhaps we would have to enlarge/stretch the tunica as well.
My next question (amongst my thousands of questions related to PE) is how does the tunica react to stress? Does it regenerate like muscle? Or does it form scar tissue? Iguana, do you know how tendons react?
Response:
I have to agree whole heartedly. It seems many parts are affected. From what I know, the tunica is make up of tough collage fibers, which I think does not regenerate. So the process here may be damage by microscopic tears and healing in the true sense of IPR. BUT, if my understanding is correct, Modesto and I discussed the strength of scar tissue and the evidence, we believe, came to the conclusion that it is weaker that normal tissue. Given this assumption, would it not mean that over time the tunica would weaken with each addition of new scar tissue? Could it be that it is the muscle tissue (maybe also tendons and ligaments) strengthens and that this is the culprit responsible for diminishing returns?
Without turning this into another Smooth Muscle Theory thread, I think it’s safe to say that the IPR and Smooth Muscle Theories go hand in hand. In fact both types of tissue (muscle and connective) are subject to IPR healing. In addition, smooth muscle is found in almost all organs and is abundant in the vascular system. Isn’t the CC and CS basically enlarged vascular cavities? So, I think it’s safe to say that these are both valid complementary theories.
Now, my questions: : )
1.) How can we determine the substance of the new tissue (muscle vs connective tissue?) Why is this important? Because, if gains come from one tissue source or the other, even yet, a combination of both, then this could have a impact on how we exercise.
2.) How do you make smooth muscle grow? If indeed this is the source of our gains the answer could be monumental to PE. Obliviously you would have to stress or damage it. Does it respond to stress the same way skeletal muscle does? Does it get stronger when stressed? Is it possible to stress it and promote cell regeneration vs damage it by overworking and promote scar tissue? Are there any supplements that would aid in it’s growth?
3.) Is scar tissue tougher than smooth muscle tissue? We seem to have evidence that it is weaker than normal surrounding tissue but does that include smooth muscle?
4.) Suppose we build this large wooden badger.? : )
I hope this makes some sense (with the exception of question 4) and doesn’t just muddy the water. I’m going to keep digging and reading.
Remek, Keep up the great work! Modesto, still waiting for your two cents.. You guys are an inspiration to me!
Regards,
Iguana