I’m learning from you too. I’m not sure of the mechanism, although I’ve got lots of studies proving it, including rodent autopsy studies. Maybe I could pick your brain. That came out wrong, :chuckle: I should ask my NIH fish oil guy, he knows all. I’m working backwards on all this—started off with the good results in women first, and have spent the last few years figuring out how it works.
But first, study links:
Zestra—I hope this is sufficient. It’s certainly legit:
http://www.zest raforwomen.com/ … blications.html
ArginMax for Women:
http://news-ser vice.stanford.e … 6/arginmax.html
Damiana hasn’t been studied—because it’s an herbal so it can’t be patented, unlike kitchen-sink herbals like ArginMax that are proprietary blends. Only two studies have been done on damiana, as far as I know—one on rats and one on men. The rat study worked. The men’s study didn’t, which doesn’t surprise me because it’s a female aphrodisiac. Damiana is included in just about every kitchen sink herbal, including the incredibly bogus and harmful Avlimil—a kitchen sink herbal promoted with a false pseudo-medical advertising campaign and very questionable accounting practices. The Ecstasy CD I think they have some studies showing the particular sound manipulation does trigger a theta brainwave state in people. Certainly no research supporting an increase in libido from that particular CD, however. Want to mention again it must be used with headphones.
But back to omega-3 fatty acids and dopamine. Why would chronically high dopamine levels be bad, if it was from a natural source humans evolved eating? Now I’m worried, because my dopamine levels are sky high. I’ve been on high dose fish oil now for seven years. No diminishing of the effect, as far as I can tell. Very healthy for you too. Only problems I’ve noticed—hard to concentrate because I want to screw all the time—sort of like being caught in some kind of male puberty phase, including a sloppy attitude toward housework and an unusual interest in porn. Also very passionate feelings. General pleasure levels much higher, which has caused some hearing loss because music is so intensely pleasurable. But that’s about it—and I think outweighed by eradicating depressive tendencies and other health benefits from fish oil.
The odd thing is that schizophrenia is actually helped by going on fish oil.
Here’s some of what I’ve got—dopamine drugs, sex and fish oil:
Szczypka MS, Zhou QY, Palmiter RD. “Dopamine-stimulated sexual behavior is testosterone dependent in mice,” Behavioral Neuroscience. 1998 Oct;112(5):1229-35.
Hull EM, Lorrain DS, Du J, Matuszewich L, Lumley LA, Putnam SK, Moses J. “Hormone neurotransmitter interactions in the control of sexual behavior,” Behav Brain Res 1999 Nov 1; 105(1):105-16.
Buffum, J.: Pharmacosexology: the effects of drugs on sexual function. A review. J. Psychoactive Drugs 14:5, 1982.
Bartlik, B. D., Kaplan, P., Kaminetsky, J., Roentsch, G., & Goldberg, J. (1999). “Medications with the potential to enhance sexual responsivity in women.” Psychiatric Annals, 29(1), 46-52.
Shrivastava, R. K., Shrivastava, S., Overweg, N., & Schmitt, M. (1995). “Amantadine in the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors.” Journal of Clinical Psychopharmacology, 15(1), 83-84.
Davidson, B. C. (2003). "Eicosanoid precursor polyenoic fatty acids modulate synaptic levels of dopamine in ex-vivo slices of rat brain striatum." In Vivo 17(1): 83-8
Logan, Alan. “Neurobehavioral aspects of omega-3 fatty acids: possible mechanisms and therapeutic value in major depression,” Altern Med Rev 2003;8(4):410-425.
Zimmer L, Delpal S, Guilloteau D, et al. Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex. Neurosci Lett 2000;284:25-28.
Delion S, Chalon S, Guilloteau D, et al. “Alpha-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotonergic neurotransmission in the rat frontal cortex.” J Neurochem 1996;66:1582-1591.
Zimmer L, Delion-Vancassel S, Durand G, et al. “Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids.” J Lipid Res 2000;41:32-40.
Zimmer L, Delpal S, Guilloteau D, et al. Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex. Neurosci Lett 2000;284:25-28.