New premature ejaculation drug
Drug could end the despair of premature ejaculation
By Jeremy Laurance, Health Editor
Published: 08 September 2006
Hope for men affected by one of the commonest and most embarrassing sexual problems has been raised by research showing premature ejaculation can be treated with a new drug.
The drug, dapoxetine, more than trebled the time to ejaculation in men taking the highest dose as well as improving their sexual satisfaction and that of their partners.
It was effective even for those who suffered the worst symptoms, ejaculating within seconds of penetration, according to the American researchers who publish their findings in The Lancet. Premature ejaculation affects between a fifth and a third of men and can lead to the breakdown of relationships.
The condition is widely under-treated but increasing numbers of men have been obtaining antidepressants, which are known to work even though they are not licensed for it.
Men taking antidepressants often report a capacity to “last” longer. But, the drugs can cause skin problems, weight gain and loss of libido.
Dapoxetine belongs to the class of drugs known as SSRIs (selective serotonin reuptake inhibitors) used in the treatment of depression but has been specifically developed as a treatment for premature ejaculation.
The study, by researchers from the University of Minnesota, involved 2,600 men and their partners, who were given either a placebo or a low or high dose of dapoxetine.
At the start of the 12-week study, the men ejaculated on average less than a minute after penetration. By the end, those taking the lower 30 mg dose were lasting 2.78 minutes while those on the higher 60 mg dose were lasting 3.32 minutes.
Jon Pryor, who led the study, said: “Dapoxetine improved patients’ perceptions of control over ejaculation, satisfaction with sexual intercourse, and overall impression of change in condition.
The drug is made by the ALZA Corporation, whose parent company is Johnson & Johnson. It is not licensed for use in the UK.
Hope for men affected by one of the commonest and most embarrassing sexual problems has been raised by research showing premature ejaculation can be treated with a new drug.
The drug, dapoxetine, more than trebled the time to ejaculation in men taking the highest dose as well as improving their sexual satisfaction and that of their partners.
It was effective even for those who suffered the worst symptoms, ejaculating within seconds of penetration, according to the American researchers who publish their findings in The Lancet. Premature ejaculation affects between a fifth and a third of men and can lead to the breakdown of relationships.
The condition is widely under-treated but increasing numbers of men have been obtaining antidepressants, which are known to work even though they are not licensed for it.
Men taking antidepressants often report a capacity to “last” longer. But, the drugs can cause skin problems, weight gain and loss of libido.
Dapoxetine belongs to the class of drugs known as SSRIs (selective serotonin reuptake inhibitors) used in the treatment of depression but has been specifically developed as a treatment for premature ejaculation.
The study, by researchers from the University of Minnesota, involved 2,600 men and their partners, who were given either a placebo or a low or high dose of dapoxetine.
At the start of the 12-week study, the men ejaculated on average less than a minute after penetration. By the end, those taking the lower 30 mg dose were lasting 2.78 minutes while those on the higher 60 mg dose were lasting 3.32 minutes.
Jon Pryor, who led the study, said: “Dapoxetine improved patients’ perceptions of control over ejaculation, satisfaction with sexual intercourse, and overall impression of change in condition.
The drug is made by the ALZA Corporation, whose parent company is Johnson & Johnson. It is not licensed for use in the UK.
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