Giving chemical PE a try

If you don’t mind. Where do you purchase your Trimix? I’m interested in trying this method out.

I have a prescription and then I have it filled through an online compounding pharmacy. I’m sure there are a ton online but the one I have been using is Olympia Pharmacy. No reason I chose them other than I found them on an internet search, but I can vouch that they are dependable, have great customer service and my orders come packed in ice within 48 hours.

Month 9 (3/24):

Trimix session days in March: 17
Total hours 90+% erection: 62.5
Total hours greater 50% erection (including above): 80

Measurements:

BPFSL: 8.94"/227mm (up from 8.875"—peak was 9" before Feb decon)
BPEL: 8.375"/213mm (no change—Peak was 8.54")
MEG: 6.375"/162mm (up from 6.25")
Scar EG: 6.125"/156mm (no change)
Base EG: 7.5"/190mm (no change)

I measured yesterday and was sub 100% erection, but I’m going with these numbers so as to not overstate anything.

Kind of a one foot in front of the other type month. Just putting in the time.

Some of the Trimix sessions were ‘just for fun’ where I inject for sex with the wife. But I still count them since I dose for a full session and have the full Trimix erection for several hours even after she tells me enough already ;)

Last week of February I started back with IGF-1 and BPC 157 for every Trimix session or every other day, depending on how many Trimix sessions I did in a row. I continued that this month.

For length: Mostly been doing hanging with FIRe, which works well while I’m stuck at my desk working, but I’m starting to experiment with high tension around the waist stretching with a new version of the waist belt I made. It is much more comfortable, durable and versatile as the original, and just as simple. I’ve used it a couple of days for my hanging session and am getting similar elongation rates so I might start transitioning to using it every day I’m not working at my desk since that buys me 90 minutes of being able to roam about compared to my hanging session and doesn’t require timing it during the day to be uninterrupted since no one knows I have it on.

Also been working a lot on girth, and I’m wondering if that is somewhat limiting my length gains. Not really sure but I’m ok with that. I’ve been clamping with cable clamps on each Trimix session and with a Python air clamp on days when I don’t do Trimix.

The Python is a little hard to figure out at first, especially with larger girth and adding the extra silicone sleeve to make the compression stronger, but once I got it figured out I’ve really appreciated it. The main issue for me is that I have to be flaccid to get into the bore of the inflatable clamp and actually vacuum pump the air out of it to wiggle through the relatively small aperture. Then once I’m in to release the vacuum, get erect and then pump it up to pressure. It works great. I can’t use it on Trimix sessions because I can’t get into it while erect even when it’s vacuumed open as much as possible.

I’ve also been pumping at least 20 minutes every day. During Trimix on those days when I can (sometimes I can’t find the space to pump while on Trimix) but always at the end of the day just before my shower.

Been doing water pumping in my standard cylinder and I have to say it’s a game changer. No lube, hot water in the tube and I’m able to work at 14-15 inHg for 2 minute intervals without significant subcutaneous edema and no discoloration. I’d get both at around 10 inHg while air pumping, sometimes with even less vacuum. So the expansion is way better and the challenges way less an issue. I definitely recommend giving it a try if you want to see how different it can be.

So in sum, just marching on, gaining mm by mm. Definitely slowed down in progress but I’m getting the sense that the next period might be more about cementing than actually gaining, but we’ll see.

My wife’s family are coming to visit for a long weekend and then I’m leaving town to visit a friend for a week, so April is going to force a decon of at least 10 days. So I’m might backslide a bit again on the stats, but I am always ok with life putting a decon break in there for me.

What is your Trimix dosage and have you maintained that dose?

Good work!

Thanks!

Currently I’m dosing 1.6mcg PGE-1 in the Trimix to get 3-5 hours of 90-100% effect. It has steadily crept up from 0.5mcg over the 9 months. Some of it is likely less sensitivity to the PGE-1, since that is a common experience, but it also could be that the vial I’ve been using is now near the end and is fairly old, even though it has been in the freezer except to draw up a week or so’s syringes.

Just updating to say that I’m still going, but slowing down a bit on my approach. I feel like I’ve cemented (or close to cemented) over 8.25" BPEL and I’m consistently just under 6.5" MSEG. Some days I’ve measured 8.5 BPEL and my base girth is over 7". I’m happy with that, as is the wife based on her responsiveness and newfound willingness to flirt with me about how big I am.

I feel like I’m plenty large and the gains are starting to come in really slowly at this point.

I could double down and find new ways to go hard at enlargement, but because I’m happy and it’s springtime with lots of fun outdoor stuff to do, I’m ramping down my efforts a bit, at least for now. My plan is to use Trimix for fun with the wife on the regular and occasionally for girth training, and to keep at more minimalist length and girth training with some more user-friendly modifications and longer periods of less-is-more approach.

So recently I’ve been using my belt ADS set up at medium high tension for about 2 hours a day (rather than being stuck at my desk with my hanging setup) and doing some mixed pumping and clamping for 10-30 minutes a day most days. When I’m stuck at my desk working (which is part time at this point in my life where I work a week or two and then have several weeks off) then I’ll do some actual hanging.

I plan on updating stats about once a quarter or so, or if I dive back into an intense phase again, which based on my history, could be in a few months, lol.

I think I can slowly gain over time, but having no set goals makes it easy to just keep on going at a lower intensity now.

I’ll keep adding to this thread over time, but I think I can say that Trimix definitely assisted with girth. My girth gains were pretty fast, steady and seem lasting. Length feels like it is less affected by the injections, but it has to be helpful in cementing new length from hanging and extending since the recurrent, prolonged erections are likely fortifying.

Overall, for me, the Trimix experiment has been well worth it. I’ve learned a ton, enlarged a bit and had a lot of fun with it. It’s definitely not for everyone, but for the right person it is worth a shot (ba-dump-bump!)

Are you referring only to the PGE-1 component? Most trimix doses start at 5mg up to 50mg.

You have had great success!

Thanks! It’s been a fun and successful experiment for me.

I am referring to just the PGE-1 component. I just use the PGE-1 dose as a shorthand.

Hey Tenacious, this is an incredible thread so thank you for all your efforts to see this through and reporting back in so much detail.

Would you be able to comment on where you have found your girth gains have come from? Do you find it is a true expansion of your CC, or is a significant portion of the girth due to expansion of the CS and the surrounding tissues? Presuming your CC has been the main contributor to your mseg expansion, is it a uniform increase in CC girth from top to base, or have you found that some area has expanded more proportionally than another?

Lastly can you say more about the slight erect bend/expressive manuals you were adding in and how you feel about those as a way of applying expansive stresses on the tunica? Do you feel they were helpful?

I use a form of erect, expressive pressure holds/bends that really target the tunica (they create incredible internal CC pressure) while sparing the surrounding tissues. It makes my tunica ache in a way that nothing else really can. I believe it is a highly effective manual method for the time spent doing them, and can only imagine Trimix would make them even more effective.

I’m glad you found it helpful. I was really inspired by Stagestop’s thread and his generosity to share, so tried to offer a similar one.

I’m one of those guys with a big CS. The underside of my penis is really full and has a contour that expands towards the region of my circle scar then narrows again toward the tip, as seen from the side. So while I think there has been some expansion there over time, as many guys have found, enlarging the CS and glans is slow because there is no tunica to work against. But I do think it has enlarged with clamping and pumping, at least some. I’ve also noticed that my expansion in a cock ring is greater than it was before dedicating to so much girth training, so functionally it has increased capacity since I always wear one during sex with my wife.

But the permanent gains were mostly CC, and the gains were pretty uniform. I’ve always been much thicker at the base and narrowest at the retroglandular sulcus, and that remains. But the gains are present all along the shaft.

Looking at my logged stats the number in inches also varied, with the measured number increasing as girth gains at the base compared to the mid shaft, and more midishaft compared the scar region. But in calculating percentage increase, as of my last official measurement in April, my base girth increased 20%, my mid shaft increased 21 %, and my scar girth increased 12%. So while the distal part of my penis is relatively smaller in circumference and gains, the overall shape is similar.

Incidentally I gained about 10% more length, but I think that is about the elongation work and more typical for the amount of effort I put in than the higher percentage gains in girth, which are typically harder to achieve.

I did some erect bends while on Trimix, but only at the end of the session as things were detumescing, and not super regularly. I do them a bit when I’m clamping without Trimix, though, as a way to increase tunica pressure near the end of the set as the penis gets fuller but slightly softer than at the beginning.

Pretty much any girth work during 90%+ Trimix erection is really, really challenging as it is very uncomfortable. I think it is also super effective, which is why I put myself through it.

So I did some gentle clamping and pumping each session when things were peaking, but hoo boy, it isn’t fun. I was always clock-watching to get through the ten minute sets and trying to keep my shit together and not stop early. So I didn’t do bends very much (essentially not enough to be meaningful) during that period of Trimix sessions. I can’t recall if I reported doing them, but if I did it was an experiment I rarely repeated.

BTW, I’ve gained a bit more in both since my last official measurement, but the length gains have slowed a lot. I’m actually thinking of focusing more on length since my girth seems to respond really well and I’m already pushing the edges of ease of use with the wife, girth-wise, though I think I could still gain a bit more anterior shaft girth and not have issues. The reason I want a bit more length is the proportion; the girth makes it appear a bit shorter than I like from an aesthetic point of view, and also my wife is very tall so has a nicely long vagina, and I know I have some room in that dimension.

I’ve read some mentions of length being harder to add when you already have meaningful girth because there’s more to stretch. I feel like it’s definitely less of a gain for me than girth, at least with my current routine. What are your thoughts? I’ve read maybe 1/3 of this thread, and you have done plenty of manual work and ADS, so what will you change to de-emphasize girth gains?

I am considering doing less frequent girth work and more hanging or extending. I tend to do at least a little girth training ever day, even if it’s just 10 minutes of soft clamping.

But honestly I really prefer girth training to length training. So perhaps I’ll just keep on keeping on.

Tenacious can you say a bit about how you injected and any learnings you had around that? There is concerns out there about fibrotic build up in the tunica round the injection sites for example, have you noticed anything unusual that might point to something like that happening?

Also can you say more about how you scheduled your erect time in, and how you avoided life in general interrupting. What did you do with the time you had a raging erection? Is it possible to sleep while on Trimix and did your wife know and approve of your special efforts?

It looks like the sheer number of hours erect must have been an important contributor to the dilation in your CC, would you agree with that or are there other considerations you feel should be acknowledged?

Could you also say more about how responsive your d is to erections now without chemical stimulants? I wonder what building a tolerance to any number of things, including Trimix/aprostadile might affect while being off them.

This is a really important post as it shows a fairly straightforward path to significantly increasing CC girth in a reasonable amount of time, which is one of the most challenging aspects of PE for various reasons. You could literally write a book on this!

Sorry to have not responded more quickly—this came in just as I was out of town with family on vacation.

I have a medical background, and also have been self-injecting testosterone replacement and many health and wellness-supporting peptides for a long time, so I’m very comfortable with careful technique and sticking myself pretty much anywhere. For a novice there is a steep learning curve, so I would encourage anyone thinking of this to learn from a healthcare professional to prevent issues.

The things I do to prevent scarring/fibrosis are to use a syringe where I can change the needle I use to draw up the Trimix, use the smallest needle to inject (that is virgin so as sharp as possible), and to rotate injection locations from side to side and up and down the shaft to ensure I’m not hitting the same spot over and over.

I also take BPC 157, a peptide that is supposed to help prevent connective tissue scarring, along with oral PABA (1g three or four times a day), which hopefully also help keep things from scarring, and might also help with tunica pliability. There are other benefits to both for an aging athlete, so it’s all benefit and I’d be taking them, anyway.

I have a couple of approaches to session timing. The first is when I’m alone for many hours, which happens quite a bit while I’m working nights or transitioning into working nights (I have a work from home overnight desk job). I am often awake by myself the whole night, so I would just inject then and have an erection for a bunch of hours. If I was not working (but staying up to get ready to work) I’d get in a lot of girth work on Trimix. If I was working, I could usually sneak in a bit of pumping and clamping, but mostly I would just ride the erection. I haven’t done this since kind of completing my experiment, since I’m no longer striving to gain rapidly.

The other way I’d schedule it, which is now my most common way, is my wife gives me an indication that she is feeling frisky and I’ll inject as soon as she’s let me know she is interested. She’s often giving me a 30-60 minute warning since we might both be involved with something that needs to be wrapped up, so I’ll inject and ride the erection until we meet up, spend an hour or more with her, then ride it until it passes. Sometimes I’ll be able to do a little pumping or clamping before we meet up, sometimes after, but usually I just let the erection support my ongoing PE work and leave it alone until it fades.

I think (based on speculation, so take it for what it’s worth) that the hours of super hard erection with Trimix are the main factor for gains, so up to a point, more is better. But I also suspect that these depend in some degree upon the length and girth work you’ve done before, during and after Trimix sessions. That is, I would typically do some elongation work prior to injecting, inject Trimix, do some really uncomfortable girth work, and then just ride the erection until it faded (or until I was so done with it after many hours that I reversed with a phenylephrine injection). Point is, I think it’s a bit like anabolic steroids: won’t do too much for muscular development without the training stimulus, but if you put the two together you can gain beyond natural by a signifiant degree. But again, that is just speculation.

I do think pumping and clamping under Trimix intensity does also make a big difference in girth gain potential that is beyond just the support it offers after pre-injection training, but as with everything else, this is speculation.

What little anecdotal data there is does seem to point to a relationship between duration and gains, though some anecdotes also suggest that even 50% Trimix erection time is valuable, so long duration 90+% erection doesn’t have to be the only consideration about dose. I keep track of 90+% and 50% in my log.

I don’t have any problems at all with non-trimix erections. I am on daily Cialis (for a variety of health benefits, as well as function) but that is because I prefer it, not because I need, though I suppose that could be confounding. I’m also on TRT with a super high libido (both at baseline and now even more with the TRT), short latency, capacity to multiple rounds every day and extremely responsive erectile functionality. So it’s difficult to exclude my baseline function supplemented by TRT as also possibly confounding.

One thing I can say is that I really enjoy sex while on Trimix. It has spoiled me a bit. While I don’t need it, the level of ongoing super hard erection is off the charts, comparable to the highest level of excitement I’ve ever reach during sex, which without Trimix naturally waxes and wanes a bit during a normal sex session. But on Trimix it’s 100% from the jump and it goes on from the moment we start until well after we’re done, sometimes hours. Super easy to go multiple rounds, though my poor wife usually taps out from satisfaction before that. So though I won’t say I’m dependent, I do really enjoy using it when I have a little heads up about upcoming frolic (and I don’t have to go out in public for a few hours after :) . I also justify it by thinking of it as supportive to my PE goals and maintenance, so win-win.

Oh, and i tried to inject a lower dose before sleeping once, but I kept waking up with a raging, nearly painful erection, and had to reverse it after about 7 hours. I think the parasympathetic state of sleep makes responsiveness way higher. I thought about playing around with decreasing dosage, but honestly it wasn’t worth it for me. Sleep is too valuable and I’d rather miss a session than deal with a bad night’s sleep.

But for some guys that might be a way to go, as long as you have your dose dialed in and a reversing agent on hand in case it goes on too long.