Giving chemical PE a try

Thats not IGF-1 though. That is either IGF-1Lr3 to IGF-1DES which are completely different things.

Correct, and I made that distinction early in my thread, but thanks for keeping me on point. I shouldn’t have used a shorthand.

I know you know, but is easy for new members or these young desperate kids trying something crazy and someone might get his hands on real IGF-1 and suddenly drop into a hypoglycemic comma before can make it to the kitchen for some sugar.

Can you maintain an erection without help? To truly test if this works you will need to go off everything for at least 8months and document if gains remain or not.

Td-

What you mentioned about cialis daily benefits beyond ed. Im interested in your thoughts about its help for other things?

Taladafil - Cialis - is sometimes prescribed as a treatment for BPH, Benign Prostate Hyperplasia. Basically, "enlarge prostate", which is very common for men over 40 or so.

I don’t know what you mean about try testing if this works. I got significantly bigger, with the caveats I mentioned in the thread, and I’ve kept that size since stopping the protocol. My dick functions normally. I don’t require any pharmacological assistance but use some for other benefits.

I also don’t know why you say I need to go off everything for at least 8 months. Seems rather an arbitrary period, unless you have some evidence basis for this assertion.

Happy to hear why you say this, but sounds like opinion rather than based on anything more concrete.

I don’t use it for erectile dysfunction, but it definitely helps with responsiveness to sexual stimulus and I seem to be much larger flaccid. Both unnecessary but nice. It’s helpful with PE and I think with PE recovery. But for the other general health reasons I take it daily:

It may provide neurocognitive protective effects with long-term use:

Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease: A Cohort Study - PubMed

Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders - PubMed

Tadalafil crosses the blood-brain barrier and reverses cognitive dysfunction in a mouse model of AD - PubMed

The Effect of Daily Low Dose Tadalafil on Cerebral Perfusion and Cognition in Patients with Erectile Dysfunction and Mild Cognitive Impairment - PubMed

It decreases pulmonary blood pressure, which protects the right heart. I also take a low dose beta blocker to improve the arterial/ left heart side of the cardiovascular system :

Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review - PMC

Finally, I’m on testosterone replacement therapy, so I’m almost certainly going to have some prostate enlargement over time, and as Andy said, it helps with urinary tract issues related to benign enlargement of the prostate:

A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction - PMC

Incidentally, it also might improve sperm quality and increase semen volume a little bit:

Once-a-day Tadalafil administration improves the spermogram parameters in fertile patients - PubMed

There might be other benefits that come to light in the future, but so far, I’ve not seen any research-backed negatives in patients who otherwise tolerate it well. So I take it as part of my extensive healthsapn/ lifespan regimen.

Do you think 12 weeks is enough to see benefits? as I might try this to help with girth routines.

Love your thread though, it’s what got me into the growth factor side of things

While I can’t say how things will be for anyone else, when I look back at my logs I gained about 0.5" of girth in the first three months. My total experiment was about 10 months and there was a plateau after the first three months that didn’t really take off again until month seven, so a three month experiment might make sense when using my single person data point as a possible guide.

Be sure to let us know if you give it a try.

I’m currently on a monthlong decon through next week, where I’ll start up again with non-chem PE. But I’m thinking of doing another 3-6 month stretch in the winter of next year, so perhaps I can say if that kind of growth is repeatable for me.

Thanks for the kind words. I was much inspired by stagestop’s thread and the more guys report on what they try after being inspired the better!

I will do 👍
I struggle with getting myself up so hopefully this helps with my current routine.