Giving chemical PE a try

The last two days I’ve woken up while I’m sleeping and in the morning with a 100% erection. I’ve had a feeling of fatigue that is similar to the Trimix sessions, which I’ve never experienced from a spontaneous erection and makes me think it might be that I’ve had the erection all night.

The morning erection won’t deflate for more than an hour and I had to get into the cold plunge both mornings and came out of 36 degree F water with an 85% CC erection that takes another 15 or 20 minutes to come down. Today I had sex with my wife after walking around with the erection I woke up with for about an hour, and it was still up until 20 minutes after the post-sex cold plunge.

I stopped cialis 2 days ago. And I skipped Trimix yesterday since I wasn’t sure if it was a lingering effect. So it had been 48 hours since cialis and 36 hours since Trimix.

I have no idea what is going on except that my EQ is off the charts. Perhaps this is a version of the ‘sausage effect’ stagestop mentions after using IGF-1 for a bit. I wonder if it is improving cavernosal responsiveness and also the increasing CC sinusoidal tissue creates circumstances that make it harder to deflate as the tunica hasn’t had time to stretch to accommodate it yet. I haven’t measured yet, as it has only been 3 weeks of IGF and 9 days of Trimix but subjectively it seems I’m a bit longer and noticeably thicker.

My wife has noticed. While we were kissing in bed during foreplay she was stroking my cock while and referred to it as ‘giant.’

Going to go for a low dose of Trimix today (0.3mcg) and it’s my IGF day. So let’s see how this goes…

My last two Trimix sessions before today were underwhelming. After taking a day off I started with a super low dose, 0.3mcg. I got a good response but it only lasted 30 minutes, which was long enough to get my pump workout in. There was definitely much more fullness than usual as a lingering effect after the erection subsided, but the session was clearly over early.

I increased a bit more the following, to 0.5mcg, which has previously given me 2-3 hours, but it, too, was less than I expected. I got about 45 minutes of 100% and then about another hour and 15 minutes of 75 percent or so. I did end up having some fatigue and tunica soreness after both sessions, but I’m not sure if that was related to expanding my already well-worked tunica or was related to the day’s session.

I made the most of both post-Trimix sessions by spending 90 minutes to 2 hours after deflation in my extender, which I apply traction enough to make me want to take it off every 20-30 minutes. As a little note, I added some tension springs to the basic LeLuv unit to add a little more tension potential as things stretch a bit, which I’m hoping makes little ongoing adjustments unnecessary, as a little too much tension from spinning the screw nuts can sometimes mean tipping me over into enough discomfort to end a session.

Another interesting note is that I’ve had that same 100% CC erection that I posted about the other day every morning for that last 4 days. It takes two hours or more to deflate, and so far the only thing that brings it down is a 36 degree F cold plunge for 3-4 minutes (from which I emerge still having the erection!) and then a brisk uphill walk for 20 minutes or more. Today I again walked around with it for an hour after waking, had sex with my wife after coffee and a chat, then did a cold plunge and even then it took about 30 minutes for it to come down fully while I was out hiking a trail.

On the one hand it seems like a beneficial session, given the theory of expanding the tunica with pressure from extended erection. But on the other, I’m trying to figure out what I’m going to do if I have to interact outside of my house in the first couple of hours of my day. Could be embarrassing and uncomfortable. I suppose I could always take some Sudafed or even inject some phenylephrine if timing was an issue, but so far I’ve been more interested in seeing how to work with it without medication intervention.

Of note, I am not getting an irreversible erection at other times of day once the morning one finally goes down. It’s just a wake up thing. At least so far.

I’m on a long stretch of work from home, so I’m going to let things ride for now, but at some point I might have to take a break from IGF-1 or even back off my TRT dose. I might even add oral finasteride back in just to calm things down a bit. We’ll see and I’ll update as things happen.

A happy note is that again today my wife made a comment about my penis size. While we were getting into it she was stroking my cock and said "Jeez, do you have a license for that thing?"

Lastly for today’s update, I injected 0.8mcg of Trimix this evening and got a perfect 2.75 hour 100% erection session, though that did require some intermittent stimulation. So the lesson I’m taking from the last few days is that while patterns are emerging in terms of dose-response, I still have some data to gather to dial things in with reasonable confidence.

I wanted to go a couple of days to make sure it was a pattern, but the unyielding am erections have stopped for the time being. Today was the third day without it happening. I had a normal morning erection that deflated right away 2 of the three mornings, and none on the other morning.

I’m still playing with Trimix dose to get an optimal duration and intensity of erection. I have read that some of the experiments haven’t required 100% intensity, but rather 40-75%, for 2-4 hours. I’ve easily gotten that every session. And way more. My last two have been 90-100% for around 5 hours. I like the idea of going hard (pun intended) at it when I have the time and privacy in order to optimize the session and potential results, but I’m finding anything above 3 hours at 90+% gets pretty uncomfortable. So while I might go for an intense session now and again, I think my approach will be to downshift for a more sustainable long-term strategy.

At this point I’ve done 13 Trimix sessions in 14 days, with a total of over 46 hours of 90%+ erection and about 58 hours of total effect time (I use approximately 50%+ as this marker). I have the time and space to continue uninterrupted daily session for another 2 or 2 1/2 weeks, and then I’ll have to downshift to 3 or 4 times a week for shorter, less intense sessions for a few weeks.

IC IGF-1 LR3 10mcg injections continue every other day.

I wanted to just comment that this thread of yours is both excellent and fascinating, as is all of your post history.

Would you mind giving us an update on your current age, starting and current stats? I see you have been around PE since there early 2000s - I have too and am nearing 40 now.

All the best on your delux PE efforts it sounds like a blast. Rooting for you!

Thanks for the compliment, WB.

I’m 50 years old. As I’ve mentioned, I’ve been a long-time but fairly intermittent PE’er, mostly because I’m pretty satisfied with my size and EQ and I go through periods of inspiration that lead to periods of PE efforts. I’ve also gone years between those periods. Life has always come first for me.

I started around 7.25 BPEL x 5.25 MEG, and have gotten as long as a bit over 8 BPEL when I’ve been consistent, but my baseline seems to drop to 7.75 when I’m not actively doing PE. My girth is pretty stable. I’m just over 5.5 mid-shaft but over 6 at the base. In a c-ring I’m up in both length and girth about 1/4 inch.

My early gains came fairly easily and quickly, and then slowed a lot. Up to now I just haven’t had the motivation to make the kind of sustained effort that would break me through this barrier. But so much has come forward in the 20 years since I got on this board (crazy that I’ve been around that long…): so many more choices for better and cheaper equipment that is so much easier to obtain, so much more experience in techniques, so much more scientific mindset about these efforts.

I don’t know what inspired me to try chemical PE. Just thought it was the last frontier for me to experiment with, and now that I have time and resources I thought I would give it a try. I think the hope is it might be the secret sauce to break through my gain barrier at the level of PE work I’m willing to devote myself to. If this works, great. If not, it’s been a fun experiment and we can add my data to the chem PE pile here at Thunder’s. Plus this latest effort has brought benefit outside PE. I’ve been able to cheaply add US and NIR (thanks, amazon) that are also nice to work with as a 50 year old athlete with lots of recurring aches and pains from weight training. Plus chemical PE folds in nicely with my anti-aging hormone and supplement therapy. So I’m going to give it a go, document along the way and see if it works to help me break a long-standing barrier.

I have to admit that if it does even partly as well for me as it did for stagestop I’ll call it a success. He claims to have gained 2.25" in BPEL and 1.5" in EG. Although it would be fun to see that kind of gain, I definitely would be happy with much less.

Thanks again, WB, for the kind words and encouragement. If I get to your size I’ll definitely consider it a success!

I’ve been continuing on with the same program and have now injected Trimix for 23 of 24 days. My total 90%+ erection time has been 80 hours and total >50% has 104 hours.

This doesn’t include the spontaneous night time and morning erections, which I mentioned above. For a while they resolved, but they’ve been back for the last five mornings. They last as long as 2.5 hours after I get up, and most early mornings I find them present when I wake up to go to the bathroom for at least a couple of hours before waking up for the day. I can’t say for certain that they are continuous while I am not awake, but I suspect they are as the feeling of mild tunica fatigue is there in the first hour or so after I’m awake, which correlates with the feeling I get around the three hour mark on Trimix.

So some of them might be present for as long as 6 hours total. This is unrelated to the Trimix sessions and many hours after Trimix detumescence.

I have no idea why this is happening except they are exactly like the Trimix erections with 100% tunica rigidity and variable CC/glans rigidity, depending on arousal. No amount of distraction or other activity causes them to go down. Post-sex, still there. Post Three minute 36 degree F cold plunge, still there. 100% CC rigidity.

I’m still thinking it might have something to do with the IGF-1 causing inner structure smooth muscle hypertrophy which might make a normal morning erection so firm against a limiting tunica that detumescence is compromised. I’m also wondering if the waxing and waning effect of this phenomenon coming and going might be the tunica slightly expanding after a few days of straining erections so that the blood flow dynamics returns to normal, and then slow increase in CC smooth muscle after a bit more IGF-1 starting the cycle over again.

I can’t know for certain. One indicator might be girth gains, but I’m waiting to measure until August.

Another interesting thought about the spontaneous erections is that one of the proposed mechanisms that enable growth from chemical pe is prolonged tunica strain from inner pressure over a long period of time. Like clamping, but without the external device. If that is so, then the night time prolonged erections (transitioning into several hours in the morning) would be like a second session for that 24 hour period. So perhaps it is a benefit to the program.

Continuing with ~30 minutes manual stretching, ~30 min low pressure pumping on Trimix and an hour or so of ADS each day. I added some Trimix clamping as a gentle addition and as long as I keep it low key it seems workable.

Subjectively it does seem like there has been some increase in length and girth, but we all know how that can be more apparent than real. The truest test will be measurements over several months. But I can say that I’m enjoying the process now that I have more confidence with my Trimix dose so whatever the ruler says it will have been a fun experiment.

Great work!

I’m real happy I stumbled upon this thread.

I was diagnosed with MS about two years ago, oddly the first symptom I noticed was the quality of my erections were iffy. Two years in I’m still largely functional, I walk funny and sometimes my brain doesn’t know where one of feet is so I’ll take a spill. Still capable of getting a decent erection but keeping it is often problematic. My neurologist gave me Rx for Viagra but that didn’t work, she said it’s cause I have a nerve problem not a circulatory problem. But reading this reminded me of a series of YouTube videos a guy made after he was paralyzed in a motorcycle accident and in one of them he talked about using TriMix so he could have sex with his wife.

Thanks for the posts everyone. Reading here gives me some hope.

I’m glad the post reminded you about injectable solutions to ED. It sounds like it might be perfect for your situation. Once you get your dose right and used to the injection technique it is really easy to use. You might need a urology consult since most general docs aren’t familiar or comfortable with dose titration in the office.

Actually after reading your post I did a search for TriMix in my town. Looks like there are a number of places (most of em telemedicine) that offer it. Haven’t gotten around to actually digging further cause I’m gonna guess that they’re real expensive, but it’s a start.

Thanks again.

I imagine if you have ED related to a diagnosis of MS then insurance should cover it. It might be less hassle to go through a specialty online telemedicine company, but those guys usually require full payment. Might make sense to go the traditional route if expense is an obstacle.

Yeah, but it’s also that the ED is transitory depending on whether or not the MS is in full swing or mild or I’m in a stable remission. When things are going my way, I have no problem getting hard, (but it sometimes takes consistent manual or visual stimulation to keep it up).

My employer doesn’t offer health insurance so medical expenses come out of my pocket. At this point I think that using TriMix is relegated to a mental wish list but at least your post reminded me that there are alternatives when I become less functional. Though the selfish side of me wants to jump right in, right now.

Again, thanks for your post. I had forgotten about that guy’s YouTube videos so next time I’m feeling like a loser I’ll remind myself that there is a treatment out there.

Took my first measurements since beginning this experiment.

After Trimix injections 29 of 30 days for a total of just under 107 hours of 90%+ erections and greater than 50% erection for just under 135 hours, and IGF-1 LR3 injections every other day.

I’ve definitely gained.

My BPFSL is increased 1/4"
BPEL is increased 1/8"
MEG is increased 1/2" (further forward the girth gain was 1/4" which results in me evening out a bit. Base girth was up 1/2")

I suspect some of the girth gains are lingering from the last workout 24 hours ago but overall it definitely seems girthier all the time.

These might be understated, as I always seem to have trouble getting fully erect to measure, so I can clearly state this level of length gains as conservative.

I have also spent approximately 30 minutes a day manual stretching, 20-30 minutes a day pumping at low pressure while on the Trimix, and averaging about 45 minutes in an extender, though the extender has been inconsistent. I’ve also started clamping for 20-30 minutes while on Trimix (before pumping) but this is just the last several days.

So it is not yet clear if gains are related solely to a return to general PE and all the methods I’ve brought back in or if the extended hard erection time has played a role in supporting as a kind of inner ADS.

It’s also too early to call the gains cemented.

The intensity with which I’ve been able to go at this for a month has been related to an extended remote work schedule, and is not sustainable for the long term. Starting August I’ll have to pare it down quite a bit. But I wanted to see if there was any promise to this technique, and so far I can’t say it doesn’t work.

I’m thinking that now that I have a good idea about my dose-response, I can start to inject before bed and let the erection ride through the night. I can titrate to avoid any risk of priapism complications.

I’ll also have to pare down my exercises, so we will see if the gains continue, or at least don’t regress.

Based on my schedule I will have periods where I can devote the same intensity so this will be a natural experiment with periods of increasing and decreasing time and intensity. We’ll see how it goes.

One thing to mention is I understand why historically a lot of people drop out of chemical PE. It is really intense and sometimes nerve-wracking. The erections go from kind of amazing to behold to uncomfortable over a few hours and I’ve often stared at my unit wishing it would just finally go down already, and wondering if I need to inject a reversing agent, which I’ve had to do a few times. The fatigue is pretty intense.

So another experiment might be to target a lower erection intensity and see how that contributes. If it is effective it would be much more sustainable over the long term.

But so far things are seeming to hold some promise.

Congrats on your gains. Even though I’m not interested to use chemical PE this is really interesting to read. Good luck with the next phase.

Did my first attempt with pre-sleep Trimix. It didn’t go as expected.

The dose I typically and consistently use for a 3-4 hour erection woke me up at 5.5 hours at 100% with no typical signs that things were on their way down. I tried to ride it for a little more than an hour but then ended up reversing it out of both fatigue/discomfort making it impossible to fall back asleep and out of an abundance of caution.

Not sure if the apparent overdose is because of hormonal and/or blood flow physiology being different at night, with the typical nocturnal erection cycle having an affect, along with being in relative parasympathetic state while sleeping. It went down quickly after reversal and then I woke up with a 100% morning erection that took about an hour to detumesce. This second one I had noticed a few times while I was in and out of sleep in the last hours of the night, so I think it was at least a couple of hours before getting up. So that means 8-9 hours of target intensity erection. Probably too much of a good thing.

I am going to have to re-order some phenylephrine to reverse to have on hand since my vial is getting low. While I think I halving the night time dose should be perfectly safe, I’m not willing to take the chance. So I’ll be taking a couple of days off injecting Trimix until it arrives.