Latest clinical results from Restorex.
https://pubmed. … h.gov/33223425/
Key takeaways:
"6-month (n = 64) and 9-month (n = 63) outcomes were reported, with a mean duration of PTT use of 31.1 minutes. No significant AEs were reported, with temporary erythema and discomfort being most common and resolving within minutes. On intent-to-treat analysis, control-to-PTT men experienced significant length (1.7-2.0 cm) and curvature improvements (18-20%). PTT-to-PTT men also achieved additional length (0.6-0.8 cm) without further curvature improvements."
So there was additional length gains from 6-9 months of .6-.8cm. So some diminishing returns but progress was far from halting.
These finding are consistent with Kyrpa’s conjecture that the volume and intensity of work needs to be modulated to avoid strengthening and thus shutting down the adaptation.
Levine had done a study some time ago in which every 2 weeks a .5cm rod was added to the extender and after 3 months found that only those that averaged over 3 hours daily had clinically significant results. So low tension needs more volume.
In the Restorex trial those doing 3 30 minute sessions did not experience additional gains. So high tension needs time under tension modulated.
I think that the body of work here has anecdotally revealed that. It’s just that there has been no standardized approach with a big enough "n".
If you’re doing long duration and not gaining, tension is probably too low. If you’re doing high tension and not gaining, the volume is probably too much.
In terms of any clinical studies considering deconditioning, good luck with that. We are on our own.
About the best I can offer, is if you really pull a hamstring it takes 6 months at least to fully heal. Is that the same deal here? Can’t say.
Is the 240 day valid for mechanotransduction? I have no fricken is all respects LOL.
But that said, if you think about your approach and you’re intelligent about it you should be able to get something.
62 achieved over 2cm in 9 months in the Restorex trial. That’s a lot of validation for an average of 31 minutes of daily use!!!