My personal opinion of Avant is that they are not worried about the safety of their products as much as results. This is made clear by Par’s almost recommendation of MDMA (ecstasy) in issue #14 of their magazine. Arguing for this drug will wear on your credibility.
Gel #3 seems to be a site specific transdermal. I dont personally know of the credibility of his statement. I would say that it will most definitely increase the risks ten fold. Add in 3alpha and you have a good possibility of prostate enlargement. 4ad would have a slightly safer effect but also dangerous since the prostate has its own 5ar. Also the fact you need to mix this yourself, with a powder, brings even more risks. I don’t recommend doing this for these reasons.
The penetration enhancer you posted that link to could be VERY uncomfortable for a sensitive region such as the penis. Jones claimed success with IPM and this would be a better choice to use than the unknowns. Jones posted a link on where you can get IPM.
MSM is also considered to be a penetration enhancer but it seems to lower the activity of enzymes which would be counter productive.
Please don’t try to be a chemist and attempt this route. You taking more chances than might be necessary considering the low amount of results from 4aderm. What I am saying is that no one has claimed good results as of yet so why take more risks when the results are unproven?